Muscle Neoplasm — Genomics

Muscle Neoplasm — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

4 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Pediatric Rhabdomyosarcomas (MSK, JCO Precis Oncol 2023) rms_msk_2023MSK

24 cases with simple somatic mutation data · 24 cases total · 2026-01-16 · mapped to Rhabdomyosarcoma EXACT_IDENTIFIER

cbioportalObserved20 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	MED12	Ssm	3	24	12.5%	cbioportal
2	MYOD1	Ssm	2	24	8.3%	cbioportal
10	KMT2B	Ssm	1	19	5.3%	cbioportal
18	TP53BP1	Ssm	1	19	5.3%	cbioportal
20	ZFHX3	Ssm	1	22	4.5%	cbioportal
4	ARID5B	Ssm	1	24	4.2%	cbioportal
3	APC	Ssm	1	24	4.2%	cbioportal
17	PTPRS

Data updated 22 days agoSource updated 2026-01-16

Rhabdomyosarcoma (NIH, Cancer Discov 2014) rms_nih_2014NIH

43 cases with simple somatic mutation data · 43 cases total · 2026-01-13 · mapped to Rhabdomyosarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	NRAS	Ssm

Rhabdomyosarcomas (MSK, NPJ Precis Oncol 2023) soft_tissue_msk_2023MSK

42 cases with simple somatic mutation data · 42 cases total · 2026-01-13 · mapped to Rhabdomyosarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm

Soft Tissue Sarcoma MYOD1 (MSK, Sci Adv 2026) soft_tissue_myod1_msk_2025MSK

20 cases with simple somatic mutation data · 20 cases total · 2026-03-05 · mapped to Rhabdomyosarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	MYOD1	Ssm

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.