Gene
NPHS1
NPHS1 adhesion molecule, nephrin
Explore in graph →CI-GENE-00017064HGNC:7908 ENSG00000161270 NCBI 4868 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (11)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 37406106
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Esophagogastric Cancer (MSK, Clin Cancer Res 2023) egc_trap_ccr_msk_2023 | Gastroesophageal Junction Adenocarcinoma | Ssm | 6 | 64 | 9.4% | 80 | cbioportal |
| Rhabdomyosarcoma (NIH, Cancer Discov 2014) rms_nih_2014 | Rhabdomyosarcoma | Ssm | 3 | 43 | 7% | 7 | cbioportal |
| Metastatic Prostate Cancer (SU2C/PCF Dream Team, Cell 2015) prad_su2c_2015 | Prostate Adenocarcinoma | Ssm | 7 | 150 | 4.7% | 103 | cbioportal |
| Esophageal Squamous Cell Carcinoma (ICGC, Nature 2014) escc_icgc | Esophageal Squamous Cell Carcinoma | Ssm | 4 | 88 | 4.5% | 74 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.