| Vemurafenib studied in …STUDIED_INderived119 of 119show fewer |
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| → studied in | NCT01709292Phase 2 · active not recruiting Vemurafenib Neoadjuvant Trial in Locally Advanced Thyroid Cancer · 119 trials list this drug (19 active) | — | — | Malignant Thyroid Gland Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04302025Phase 2 · recruiting A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC) · 119 trials list this drug (19 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06561360Phase 2 · recruiting A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL) · 119 trials list this drug (19 active) | — | — | Hairy Cell Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03178552Phase 2/Phase 3 · active not recruiting A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC) · 119 trials list this drug (19 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03410875Phase 2 · active not recruiting A Phase II Study of the BRAF Inhibitor, Vemurafenib, Plus Obinutuzumab in Patients With Previously Untreated Classical Hairy Cell Leukemia · 119 trials list this drug (19 active) | — | — | Leukemia,Hairy Cell Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03155620Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) · 119 trials list this drug (19 active) | — | — | Hepatoblastoma,Malignant Germ Cell Tumor,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03181100Phase 2 · active not recruiting Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer · 119 trials list this drug (19 active) | — | — | Thyroid Gland Anaplastic Carcinoma,Thyroid Gland Carcinoma,Poorly Differentiated Thyroid Gland Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03768063Phase 3 · active not recruiting A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05525858recruiting KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04722575Phase 2 · active not recruiting Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03224767Phase 2 · active not recruiting Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma · 119 trials list this drug (19 active) | — | — | Papillary Craniopharyngioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02314481Phase 2 · completed Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity · 119 trials list this drug (19 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03554083Phase 2 · completed Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01787500Phase 1 · completed Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery · 119 trials list this drug (19 active) | — | — | Solid Neoplasm,Malignant Solid Neoplasm,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05068752Phase 2 · completed Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer · 119 trials list this drug (19 active) | — | — | Pancreatic Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02721459Phase 1 · active not recruiting XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma · 119 trials list this drug (19 active) | — | — | Malignant Skin Neoplasm,Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01909453Phase 3 · completed Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01659151Phase 2 · completed Vemurafenib With Lymphodepletion Plus Adoptive Cell Transfer & High Dose IL-2 Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06440850Phase 2 · recruiting Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation · 119 trials list this drug (19 active) | — | — | Thyroid Gland Follicular Carcinoma,Thyroid Gland Oncocytic Carcinoma,Thyroid Gland Papillary Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05768178Phase 2/Phase 3 · recruiting DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. · 119 trials list this drug (19 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Solid Neoplasm,Melanoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03498521Phase 2 · completed A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm of Unknown Primary | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01711632Phase 2 · completed BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia · 119 trials list this drug (19 active) | — | — | Hairy Cell Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04462471Phase 1 · completed Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers · 119 trials list this drug (19 active) | — | — | Thyroid Gland Follicular Carcinoma,Malignant Thyroid Gland Neoplasm,Thyroid Gland Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01748149early Phase 1 · completed Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02304809Phase 2 · active not recruiting Phase 2 Study Assessing Secured Access to Vemurafenib for Patients With Tumors Harboring BRAF Genomic Alterations · 119 trials list this drug (19 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02908672Phase 3 · completed A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01378975Phase 2 · completed A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02145143early Phase 1 · completed Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study · 119 trials list this drug (19 active) | — | — | Thyroid Gland Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03013491Phase 1/Phase 2 · terminated PROCLAIM-CX-072: A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas · 119 trials list this drug (19 active) | — | — | Solid Neoplasm,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02145910Phase 1 · withdrawn Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases · 119 trials list this drug (19 active) | — | — | Melanoma,Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02902029Phase 2 · completed Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05260684completed Comparative Effectiveness of Targeted Therapies in BRAF Positive Metastatic Melanoma in the US · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04423185Phase 2 · recruiting PLATFORM Study of Precision Medicine for Rare Tumors · 119 trials list this drug (19 active) | — | — | Rare Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03220035Phase 2 · completed Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) · 119 trials list this drug (19 active) | — | — | Hepatoblastoma,Malignant Germ Cell Tumor,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04551521Phase 2 · completed CRAFT: The NCT-PMO-1602 Phase II Trial · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06692491Phase 2 · not yet recruiting Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS · 119 trials list this drug (19 active) | — | — | Rare Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02091141Phase 2 · completed My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors · 119 trials list this drug (19 active) | — | — | Neoplasm,Solid Neoplasm,Malignant Bladder Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03101254Phase 1/Phase 2 · completed LY3022855 With BRAF/MEK Inhibition in Patients With Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05159245Phase 2 · recruiting The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs · 119 trials list this drug (19 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02291289Phase 2 · completed A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC) · 119 trials list this drug (19 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03625141Phase 2 · completed A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878524Phase 1 · terminated Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial · 119 trials list this drug (19 active) | — | — | Hematopoietic and Lymphatic System Neoplasm,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05238831early Phase 1 · withdrawn SMMART Adaptive Clinical Treatment (ACT) Trial · 119 trials list this drug (19 active) | — | — | Malignant Solid Neoplasm,Sarcoma,Breast Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04591431Phase 2 · unknown The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy · 119 trials list this drug (19 active) | — | — | Malignant Breast Neoplasm,Malignant Digestive System Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03430947Phase 2 · terminated Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases · 119 trials list this drug (19 active) | — | — | Melanoma,Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03781219Phase 1 · unknown A PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 Mutation · 119 trials list this drug (19 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05233332Phase 2 · unknown Study of HL-085 and Vemurafinib in Metastatic Colorectal Cancer (mCRC) · 119 trials list this drug (19 active) | — | — | Colorectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05263453Phase 2 · unknown HL-085+Vemurafenib to Treat Advanced Melanoma Patients With BRAF V600E/K Mutation · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04801966NA · terminated Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04790448Phase 1/Phase 2 · completed Efficacy of VIC Regimen in BRAF Mutant Metastatic Colorectal Cancer · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01657591Phase 1 · completed Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02052193Phase 2 · terminated Evaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb Study · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02036086Phase 2 · unknown Study of Neo-adjuvant Use of Vemurafenib Plus Cobimetinib for BRAF Mutant Melanoma With Palpable Lymph Node Metastases · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05019534Phase 1 · unknown Tolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal Cancer · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01689519Phase 3 · completed A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03239015Phase 2 · unknown Efficacy and Safety of Precision Therapy in Refractory Tumor · 119 trials list this drug (19 active) | — | — | Neoplasm,Rare Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01959633Phase 1/Phase 2 · completed Vemurafenib Plus Cobimetinib Plus PEG-interferon in Advanced Melanoma Patients Harboring the V600BRAF Mutation · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02818023Phase 1 · terminated Dose-seeking Study of Pembrolizumab Plus Vemurafenib and Cobimetinib Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01638676Phase 1/Phase 2 · recruiting A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03727763Phase 2 · unknown Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT) · 119 trials list this drug (19 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03224208Phase 2 · terminated Vemurafenib Plus Cobimetinib in Advanced or Metastatic Melanoma Patients · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01636908NA · completed Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01597908Phase 3 · completed Dabrafenib Plus Trametinib vs Vemurafenib Alone in Unresectable or Metastatic BRAF V600E/K Cutaneous Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02303951Phase 2 · terminated Neoadjuvant Vemurafenib + Cobimetinib + Atezolizumab in Melanoma: NEO-VC · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01531361Phase 1 · completed Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01739764Phase 4 · completed An Extension (Rollover) Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Malignancies Previously Enrolled in an Antecedent Vemurafenib Protocol · 119 trials list this drug (19 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02164916Phase 2 · completed S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer · 119 trials list this drug (19 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01942993Phase 2 · terminated The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01656642Phase 1 · completed A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01636622Phase 1 · completed Study of Vemurafenib, Carboplatin, and Paclitaxel · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01596140Phase 1 · completed Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01897116Phase 1 · completed A Phase I Trial of Vemurafenib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01826448Phase 1 · terminated A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02354690Phase 1/Phase 2 · completed Vemurafenib and TIL Therapy for Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02638428Phase 2 · unknown Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy · 119 trials list this drug (19 active) | — | — | Childhood Solid Neoplasm,Childhood Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02608034Phase 1 · completed A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01898585Phase 4 · completed An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01585415Phase 1 · terminated Vemurafenib and White Blood Cell Therapy for Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm,Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02768207Phase 2 · completed A Study to Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01271803Phase 1 · completed A Study of Vemurafenib and GDC-0973 (Cobimetinib) in Participants With BRAFV600E Mutation-Positive Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01667419Phase 3 · completed A Study of Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01910181Phase 1 · completed A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01603212Phase 1 · completed Systemic Therapy With Interferon, Interleukin-2 and BRAF Inhibitor · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01813214Phase 2 · terminated The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03139513completed A Study of Adult Participants With BRAF V600 Mutation-Positive Advanced Melanoma Treated With Cobimetinib (Cotellic®) During the French Early Access Program (Temporary Authorization for Use [TAU]) · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02050321Phase 2 · terminated A Phase II Study of Vemurafenib Combined With Acitretin in Patients With Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01673854Phase 2 · completed Phase II Safety Study of Vemurafenib Followed by Ipilimumab in Subjects With V600 BRAF Mutated Advanced Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01616199Phase 1/Phase 2 · terminated Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01943422Phase 1 · completed Safety and Efficacy Study of Vemurafenib and High-dose Interferon Alfa-2b in Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01767623Phase 1 · completed A Study of The Impact of Severe Hepatic Impairment on the Pharmacokinetics and Safety of Vemurafenib in BRAF V600 Mutation-Positive Cancer Participants · 119 trials list this drug (19 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01307397Phase 3 · completed A Study of Vemurafenib in Participants With Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01524978Phase 2 · completed A Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Cancers · 119 trials list this drug (19 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02441465Phase 1 · completed Bioavailability Study of Vemurafenib in Participants With BRAF^V600 Mutation-Positive Malignancies · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01495988Phase 2 · terminated Trial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02230306Phase 2 · terminated Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain Metastases · 119 trials list this drug (19 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02456701Phase 1 · completed Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379 · 119 trials list this drug (19 active) | — | — | Malignant Thyroid Gland Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00405587Phase 1 · completed Safety Study of PLX4032 in Patients With Solid Tumors · 119 trials list this drug (19 active) | — | — | Melanoma,Colorectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00949702Phase 2 · completed A Study of Vemurafenib in Previously Treated Patients With Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01586195Phase 2 · terminated Study Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600E · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01843738Phase 1 · withdrawn Radiation Use During Vemurafenib Treatment · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01754376Phase 2 · terminated Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01611675Phase 1 · terminated Leflunomide+Vemurafenib in V600 Mutant Met. Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01844674Phase 1 · completed A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01781026Phase 2 · completed Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain Metastases · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01765543Phase 1 · completed A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf) · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02427893Phase 3 · withdrawn Trial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01765556Phase 1 · withdrawn A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01849666Phase 1 · completed A Study of the Effect of Vemurafenib on the Pharmacokinetics of Phenprocoumon in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01851824Phase 1 · completed A Study of the Effect of Vemurafenib on the Pharmacokinetics of Acenocoumarol in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01974258Phase 1 · withdrawn Safety, Tolerability, and Pharmacokinetics of Onartuzumab Combined With Vemurafenib and/or Cobimetinib in Cancer Patients · 119 trials list this drug (19 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01519323Phase 1 · terminated BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01006980Phase 3 · completed A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3) · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01286753Phase 2 · completed A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 Mutation · 119 trials list this drug (19 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01474551Phase 2 · terminated Vemurafenib (R05185426) in Poor Performance Status Patients With Unresectable Locally Advanced or Metastatic Melanoma Harboring a V600E/K Mutation · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01765569Phase 1 · completed A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01673737Phase 1 · completed A Phase I/Ib Trial for the Evaluation of SAR260301 in Monotherapy or in Combination With Vemurafenib in Patients With Various Advanced Cancer · 119 trials list this drug (19 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01400451Phase 1 · terminated Ph I Ipilimumab Vemurafenib Combo in Patients With v-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01835184Phase 1 · terminated Cabozantinib-S-Malate and Vemurafenib in Treating Patients With Solid Tumors or Melanoma That is Metastatic or That Cannot Be Removed By Surgery · 119 trials list this drug (19 active) | — | — | Adult Solid Neoplasm,Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01841463Phase 1 · suspended Study of an Oral Cdk Inhibitor Administered With an Oral BRAF Inhibitor in Patients With Advanced or Inoperable Malignant Melanoma With BRAF Mutation · 119 trials list this drug (19 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |