Hematologic Malignancy

Langerhans Cell Histiocytosis

CI-CAN-00003004LCHExplore in graph →

HematologicNon-malignant12 active trials1 evidence items

NCIt: C3107
OncoTree: LCH
DOID: 2571
UMLS CUI: C0019621

Data completeness2 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (no data yet)
Genomics (no data yet)
Evidence (data present)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001)

Definition text as published by ncit-evs Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Tumors Derived from Langerhans CellsHematologic Malignancy

oncotree

Histiocytic and Dendritic Cell NeoplasmCancer Family

Children (9)

ncit

Anatomy

Anatomical sites

Hematopoietic and Lymphatic SystemC35813

1 sub

Langerhans Cell Histiocytosis, Monostotic2 sub

Langerhans Cell Histiocytosis, Polyostotic1 sub

18 descendants in total; counters on this page aggregate over all of them.

Publications (all / 5y)

0 / 0

Evidence items

1

Genes / variants

1 / 1

Drugs (any / approved)

1 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (3)

Histiocytosis Xsynonym · NCIt
Langerhans Cell Granulomatosissynonym · NCIt
Langerhans Cell Histiocytosissynonym · OncoTree

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials12countcurrent registry status · entity + descendantsclinicaltrialsComputednot in a current ranking snapshot
Recruiting trials3countstatus RECRUITING · entity + descendantsclinicaltrialsComputednot in a current ranking snapshot
Curated evidence items1countaccepted CIViC items · entity + descendantscivicComputednot in a current ranking snapshot
Publications, last 12 months0countPubMed records · stored query · 12-month windowpubmedComputednot in a current ranking snapshot
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 18 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants