Cancer
Malignant Rectal Neoplasm
CI-CAN-00008012Explore in graph →
Top-level386 active trials1 approved drugs5 evidence items
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Cancer
CI-CAN-00008012Explore in graph →
Clinical trials
1,549 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (153)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06540027 | The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer | unknown | — | 80 | Başakşehir Çam & Sakura City HospitalOTHER_GOV | 1 | Aug 15, 2024 | clinicaltrials |
| NCT06006390 | CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors | unknown | Phase 1 / Phase 2 | 60 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Aug 9, 2024 |
| clinicaltrials |
| NCT04636008 | Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer | unknown | Phase 1 / Phase 2 | 20 | West China HospitalOTHER | 1 | Aug 6, 2024 | clinicaltrials |
| NCT06536712 | Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection | unknown | Phase 1 | 20 | Tehran University of Medical SciencesOTHER | 1 | Aug 5, 2024 | clinicaltrials |
| NCT06524362 | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial(PERECARE) | unknown | N/A | 77 | GEM Hospital & Research CenterOTHER | 1 | Jul 29, 2024 | clinicaltrials |
| NCT06519006 | Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)(CH1) | unknown | N/A | 50 | F. D. Roosevelt University HospitalOTHER | 1 | Jul 25, 2024 | clinicaltrials |
| NCT06256055 | Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors | unknown | Phase 1 | 24 | UTC Therapeutics Inc.INDUSTRY | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06326892 | Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery(NOSES) | unknown | — | 350 | Istituto Clinico HumanitasOTHER | 1 | Jun 26, 2024 | clinicaltrials |
| NCT06458725 | Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers(PILLAR) | unknown | N/A | 30 | Jules Bordet InstituteOTHER | 0 | Jun 14, 2024 | clinicaltrials |
| NCT03992456 | Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer | unknown | Phase 2 | 12 | Academic and Community Cancer Research UnitedOTHER | 1 | May 21, 2024 | clinicaltrials |
| NCT05233787 | Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17)(GRECCAR17) | unknown | N/A | 212 | University Hospital, BordeauxOTHER | 1 | May 16, 2024 | clinicaltrials |
| NCT04755920 | SGM-101 in Colorectal Brain Metastases.(SGM-CBM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | May 9, 2024 | clinicaltrials |
| NCT06395337 | Multimodal Imaging in Rectal Cancer & Pancreatic Cancer(MIRCA & MIPAC) | unknown | Phase 1 / Phase 2 | 20 | Radboud University Medical CenterOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06380855 | Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME) | unknown | — | 5 | Sun Yat-sen UniversityOTHER | 1 | Apr 24, 2024 | clinicaltrials |
| NCT05052086 | Magnetomotoric Ultrasound (MMUS) in Rectal Cancer(MAMORECT) | unknown | N/A | 60 | Region SkaneOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT06375434 | Correlation Between Gut Microbiota and Radiosensitivity of Rectal Cancer(GMRSC-LARC) | unknown | — | 100 | Jing-kun LiuOTHER | 0 | Apr 19, 2024 | clinicaltrials |
| NCT06369597 | A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery | unknown | N/A | 177 | Sun Yat-sen UniversityOTHER | 1 | Apr 17, 2024 | clinicaltrials |
| NCT03962088 | Timisnar - Biomarkers Substudy (Timisnar-mirna)(TiMiSNAR-miRNA) | unknown | — | 200 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT04543695 | A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer | unknown | Phase 2 | 255 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT05305820 | Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy(PANO) | unknown | N/A | 36 | Dublin City UniversityOTHER | 1 | Mar 21, 2024 | clinicaltrials |
| NCT06304987 | Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer | unknown | Phase 2 | 50 | Beijing Friendship HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06318234 | PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer | unknown | — | 32 | Xiao ChenOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06311279 | End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum | unknown | N/A | 20 | Sohag UniversityOTHER | 1 | Mar 15, 2024 | clinicaltrials |
| NCT03951337 | 64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum) | unknown | Phase 2 | 70 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06304597 | Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy(PREDICT) | unknown | Phase 1 | 18 | University Medical Center GroningenOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06300489 | Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer | unknown | Phase 1 | 30 | Zhejiang Cancer HospitalOTHER | 1 | Mar 8, 2024 | clinicaltrials |
| NCT05111860 | Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy | unknown | Phase 1 / Phase 2 | 20 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Mar 7, 2024 | clinicaltrials |
| NCT04923620 | Neoadjuvant Cetuximab + Chemotherapy Combined With Short-course Radiotherapy | unknown | — | 51 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
| NCT05279287 | Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS)(VAMIS) | unknown | — | 100 | The Griffin InstituteOTHER | 1 | Feb 22, 2024 | clinicaltrials |
| NCT05980689 | Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer | unknown | Phase 2 | 33 | Sun Yat-sen UniversityOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT03799939 | Chimney Trial of Parastomal Hernia Prevention | unknown | N/A | 141 | University of OuluOTHER | 2 | Feb 1, 2024 | clinicaltrials |
| NCT03503630 | Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma | unknown | Phase 2 | 44 | Ali ShamseddineOTHER | 2 | Jan 31, 2024 | clinicaltrials |
| NCT06218108 | Multicenter Observational Study Taulí-T1 Classification for the Management of pT1 Rectal Adenocarcinoma(TAUTEM-pT1) | unknown | — | 317 | Corporacion Parc TauliOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06216834 | Quality of Life and Psychosocial Status of Young-onset Patients With Rectal Cancer | unknown | — | 300 | Shandong Provincial HospitalOTHER_GOV | 1 | Jan 22, 2024 | clinicaltrials |
| NCT05646043 | PREHAB - Improving Condition Before Surgery | unknown | N/A | 40 | University Hospital OstravaOTHER | 1 | Jan 18, 2024 | clinicaltrials |
| NCT03034473 | Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC-II-IV, With a 5-Fluorouracil-based Standard Radiochemotherapy Followed by Total Mesorectal Excision.(TransValid-A) | unknown | N/A | 200 | University Medical Center GoettingenOTHER | 1 | Dec 28, 2023 | clinicaltrials |
| NCT01477229 | Quality of Life in RECTal Cancer - a Prospective Multicenter Cohort Study(QoLiRECT) | unknown | — | 1,500 | Sahlgrenska University HospitalOTHER | 1 | Dec 8, 2023 | clinicaltrials |
| NCT04622176 | Magnetomotoric Ultrasound for Diagnostic Purposes in Rectal Cancer(MMURC) | unknown | — | 28 | Sahlgrenska University HospitalOTHER | 1 | Dec 8, 2023 | clinicaltrials |
| NCT05328960 | The Pandemic's Effect on Diagnosis and Treatment of Rectal Cancer(CovidRC) | unknown | — | 8,000 | Sahlgrenska University HospitalOTHER | 1 | Dec 8, 2023 | clinicaltrials |
| NCT03729687 | Short Course Radiation Therapy Followed by Pre-operative Chemotherapy and Surgery in High-risk Rectal Cancer(LARCT-US) | unknown | Phase 2 | 280 | Uppsala UniversityOTHER | 1 | Nov 30, 2023 | clinicaltrials |
| NCT05502354 | CRP-guided Transanal Drainage Removal After Rectal Surgery | unknown | N/A | 250 | Qilu Hospital of Shandong UniversityOTHER | 1 | Nov 21, 2023 | clinicaltrials |
| NCT04592289 | Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone(REPCA) | unknown | N/A | 622 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT04906044 | Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer(STARS-RC03) | unknown | Phase 1 | 46 | The First Hospital of Jilin UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT03607370 | Timing for Rectal Surgery After Chemoradiotherapy(ST812) | unknown | N/A | 142 | National Cancer Center Affiliate of Vilnius University Hospital Santaros KlinikosOTHER | 1 | Nov 8, 2023 | clinicaltrials |
| NCT06096493 | Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum | unknown | — | 200 | South Valley UniversityOTHER | 1 | Oct 23, 2023 | clinicaltrials |
| NCT06056726 | Evaluation of Surgical Complications and DFS in Obese Rectal Cancer Patients | unknown | — | 90 | Federico II UniversityOTHER | 1 | Sep 29, 2023 | clinicaltrials |
| NCT05176964 | Chemotherapy and Tislelizumab With Split-course HFRT for Locally Advanced Rectal Cancer | unknown | — | 50 | Fujian Medical University Union HospitalOTHER | 1 | Sep 25, 2023 | clinicaltrials |
| NCT06050447 | Factors Affecting the Results of Treatment of Patients With Colorectal Cancer | unknown | — | 1,200 | Immanuel Kant Baltic Federal UniversityOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT02031939 | Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer | unknown | Phase 3 | 556 | Sun Yat-sen UniversityOTHER | 1 | Aug 25, 2023 | clinicaltrials |
| NCT05957016 | Neoadjuvant CIETAI With Concurrent Chemoradiotherapy in Local Advanced Rectal Cancer | unknown | Phase 2 | 90 | Third Military Medical UniversityOTHER | 1 | Aug 23, 2023 | clinicaltrials |
Data updated 22 days agoSource updated Aug 15, 2024source: clinicaltrials