Clinical trial · Interventional
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
Comprehensive Assessment of Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI) Measures: Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers. (PILLAR)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates the reliability of functional MRI measurements in pelvic disease through quantifying repeatability and reproducibility, using healthy volunteers. The aim is to provide insights into the consistency of results across sessions and observers, informing the trustworthiness of functional MRI in assessing pelvic disease and particularly rectal cancers and guiding protocol optimization.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pelvic Cancer | Malignant Pelvic Neoplasm | ALIAS | 0.90 |
| Rectum Cancer | Rectal Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Magnetic Resonance Imaging (MRI) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Volunteers
- description
- Single arm of volunteers.
- interventionNames
- Device: Magnetic Resonance Imaging (MRI)
Primary outcomes (2)
- measure
- Assess the repeatability coefficient (RC) (percentage)
- timeFrame
- Day 1 and Day 10-17
- description
- Quantitative assessment of the Repeatability Coefficient for functional MRI sequences in rectal tissue, expressed as a percentage.
- measure
- Assess the reproducibility coefficient (RDC) (percentage)
- timeFrame
- Day 1 and Day 10-17
- description
- Comparative analysis of Repeatability Coefficient values obtained from distinct MRI devices, providing insights into device-specific variations.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ≥ 18 yo * Healthy * Volunteer * Ability to undergo an MRI Exclusion Criteria: * \< 18yo * Contraindication to undergoing an MRI (see safety questionnaire) * Previous pelvic irradiation * Pelvic pathology
References
Publications (0)
Data not yet available