Clinical trial · Observational
Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery
Postoperative Outcomes of Natural Orifice Specimen Extraction (NOSE) in Low Rectal Cancer Surgery
NCT06326892CI-TRIAL-00078258NOSESunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to compare the postoperative outcomes of low rectal cancer patients who underwent surgery with Natural Orifice Specimen Extraction (NOSE) versus traditional Pfannenstiel extraction.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Natural Orifice Specimen Extraction (NOSE) | Procedure | — | UNRESOLVED |
| Traditional specimen extraction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Natural Orifice Specimen Extraction (NOSE)
- description
- Patients with low rectal cancer who underwent rectal resection with Natural Orifice Specimen Extraction (NOSE)
- interventionNames
- Procedure: Natural Orifice Specimen Extraction (NOSE)
- label
- Controls
- description
- Patients with low rectal cancer who underwent rectal resection with traditional specimen extraction
- interventionNames
- Procedure: Traditional specimen extraction
Primary outcomes (1)
- measure
- Surgical Site Infections (SSI)
- timeFrame
- 30 days after surgery
- description
- Rate difference of 30-day Surgical Site Infections (SSI)- defined according to the definition of the Center for Disease Control and Prevention (CDC) \[Ref\]- between the study cohorts.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing low anterior resection with Total Mesorectal Excision (TME) for low rectal cancer between January 2017 and January 2023 * Patients with rectal cancer classified as "low" according to the English National Low Rectal Cancer Development Programme (LOREC) Exclusion Criteria: * Patients undergoing non-restorative procedures * Patients undergoing immediate or delayed handsewn coloanal anastomosis * Patients undergoing planned open surgery or unplanned conversion from minimally invasive to open surgery * Patients with a concomitant diagnosis of Inflammatory Bowel Disease (IBD)
References
Publications (0)
Data not yet available
No reference posted for this study.