Clinical trial · Observational
The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
As a hypothesis and shown in many meta-analyses and randomized controlled studies, minimally invasive surgery causes less surgical trauma and therefore less proinflammatory response and immunosuppression develop, and postoperative recovery is faster. Although various prognostic studies on the relationship between gastrointestinal cancer types and SII (systemic inflammatory index) and the use of minimally invasive surgery have been published, the high level of this response and the type of surgery in the treatment of colorectal cancer have not yet been shown to have a direct effect on SII.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Adenocarcinoma | Colorectal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Immune System Disorder | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
| Rectal Cancer Stage | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| rectal cacer surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Control group
- description
- Patients with rectal cancer, open surgery
- interventionNames
- Procedure: rectal cacer surgery
- label
- Study group 1
- description
- Patients with rectal cancer, laparoscopic surgery
- interventionNames
- Procedure: rectal cacer surgery
- label
- Study group 2
- description
- Patients with rectal cancer, robotic surgery
- interventionNames
- Procedure: rectal cacer surgery
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: Patients operated for rectal cancer * Open surgery * Laparoscopic surgery * Robotic surgery Exclusion Criteria: * Patients with diagnosed immune deficiency * Patients with recurrent colorectal cancer * Patients with co-existent tumors
References
Publications (0)
Data not yet available