| Sirolimus studied in …STUDIED_INderived200 of 230show all (up to 200) |
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| → studied in | NCT00092222Phase 2 · active not recruiting Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06876142Phase 1/Phase 2 · suspended Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07844694early Phase 1 · recruiting Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06084780Phase 2 · not yet recruiting Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE) · 230 trials list this drug (53 active) | — | — | Pseudomyxoma Peritonei | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07162038Phase 1 · recruiting Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05327023Phase 1/Phase 2 · recruiting Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05436418Phase 1/Phase 2 · recruiting The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07813533early Phase 1 · not yet recruiting A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above. · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07796620Phase 1/Phase 2 · not yet recruiting Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07725380Phase 1/Phase 2 · recruiting Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma · 230 trials list this drug (53 active) | — | — | Sarcoma,Osteosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05896839Phase 1/Phase 2 · recruiting Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer · 230 trials list this drug (53 active) | — | — | Melanoma,Basal Cell Carcinoma,Skin Squamous Cell Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01885689Phase 2 · active not recruiting Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia · 230 trials list this drug (53 active) | — | — | Myelodysplastic Syndrome,Secondary Myelodysplastic Syndrome,Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00792948Phase 2 · active not recruiting Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Adult Acute Lymphoblastic Leukemia,Adult B Acute Lymphoblastic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07582172Phase 2 · recruiting Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome · 230 trials list this drug (53 active) | — | — | Myelodysplastic Syndrome,Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06528301Phase 1 · recruiting A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies · 230 trials list this drug (53 active) | — | — | B-Cell Malignant Neoplasm,Lymphoma,Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07735533Phase 1/Phase 2 · not yet recruiting A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies · 230 trials list this drug (53 active) | — | — | B-Cell Malignant Neoplasm,Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07735546Phase 1 · not yet recruiting A Phase 1 Study of UB-VV500 With Rapamycin in Relapsed/Refractory Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07426484Phase 4 · recruiting Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy · 230 trials list this drug (53 active) | — | — | Malignant Skin Neoplasm,Skin Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03099356Phase 2 · recruiting Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer · 230 trials list this drug (53 active) | — | — | Malignant Thyroid Gland Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06287944Phase 1 · recruiting 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07715734Phase 2 · not yet recruiting Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma · 230 trials list this drug (53 active) | — | — | Skin Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01087554Phase 1 · active not recruiting Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04177004Phase 1 · active not recruiting Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07684287Phase 2 · not yet recruiting A Phase 2 Study of Sirolimus for Injection (Albumin-bound) in Patients With Progressive or Symptomatic Epithelioid Hemangioendothelioma · 230 trials list this drug (53 active) | — | — | Epithelioid Hemangioendothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07436611Phase 2 · not yet recruiting Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07656909Phase 2/Phase 3 · recruiting Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP · 230 trials list this drug (53 active) | — | — | Kaposiform Hemangioendothelioma,Hemangiomatosis with Thrombocytopenia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04083183Phase 1/Phase 2 · recruiting Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases · 230 trials list this drug (53 active) | — | — | Non-Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04959175Phase 1/Phase 2 · recruiting Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07581704Phase 1 · recruiting Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00544115Phase 2 · active not recruiting Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02583893Phase 2 · completed Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia · 230 trials list this drug (53 active) | — | — | Secondary Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03433183Phase 2 · completed SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors · 230 trials list this drug (53 active) | — | — | Malignant Peripheral Nerve Sheath Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03246906Phase 2 · terminated Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05088356Phase 1 · active not recruiting Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Acute Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06308445Phase 2 · not yet recruiting Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04888741Phase 2 · recruiting Methods of T Cell Depletion Trial (MoTD) · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01231412Phase 3 · completed Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Acute Lymphoblastic Leukemia,Hodgkin Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07165886Phase 2/Phase 3 · recruiting Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors · 230 trials list this drug (53 active) | — | — | Digestive System Neuroendocrine Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03192397Phase 1/Phase 2 · active not recruiting Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Hodgkin Lymphoma,Multiple Myeloma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02711202NA · completed Sequential Targeting of Cluster of Differentiation 52 (CD52) and Tumor Necrosis Factor (TNF) Allows Early Minimization Therapy in Kidney Transplantation · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04339101Phase 2 · completed Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Myelodysplastic Syndrome,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03970096Phase 2 · recruiting Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02574728Phase 2 · active not recruiting Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04469530Phase 2 · recruiting Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors · 230 trials list this drug (53 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05170828Phase 1 · withdrawn Cryopreserved MMUD BM With PTCy for Hematologic Malignancies · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01203722Phase 1/Phase 2 · completed Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03304678Phase 2 · completed Discovery of Sirolimus Sensitive Biomarkers in Blood · 230 trials list this drug (53 active) | — | — | Lymphangioleiomyomatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01625351Phase 1 · completed A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas · 230 trials list this drug (53 active) | — | — | Digestive System Neoplasm,Germ Cell Tumor,Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07366801Phase 2/Phase 3 · recruiting Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05104983Phase 2 · recruiting Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00975819Phase 2 · completed Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies · 230 trials list this drug (53 active) | — | — | Lymphangioma Circumscriptum,Tufted Hemangioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00133887Phase 3 · completed TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients · 230 trials list this drug (53 active) | — | — | Malignant Skin Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03983850Phase 1/Phase 2 · active not recruiting Optimizing PTCy Dose and Timing · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06799195Phase 2 · recruiting Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01869114Phase 2 · completed Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy · 230 trials list this drug (53 active) | — | — | Myelodysplastic Syndrome,Adult Acute Myeloid Leukemia,Myelodysplastic Syndrome with del(5q)+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03363763Phase 2 · terminated Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07241936Phase 1/Phase 2 · recruiting A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors · 230 trials list this drug (53 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00776373Phase 1/Phase 2 · terminated Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive,Burkitt Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06743503Phase 1 · recruiting UB-VV400 in Combination With Rapamycin in Relapsed or Refractory B-cell Malignancies · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05860881Phase 3 · active not recruiting Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin) · 230 trials list this drug (53 active) | — | — | Malignant Skin Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01737502Phase 1/Phase 2 · completed Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer · 230 trials list this drug (53 active) | — | — | Lung Non-Small Cell Carcinoma,Lung Squamous Cell Carcinoma,Lung Adenocarcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02790515Phase 2 · active not recruiting Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation · 230 trials list this drug (53 active) | — | — | Myeloid Sarcoma,Acute Lymphoblastic Leukemia,Juvenile Myelomonocytic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02793544Phase 2 · completed HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide · 230 trials list this drug (53 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Chronic Lymphocytic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04473911Phase 1 · completed Haplo Peripheral Blood Sct In GVHD Prevention · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02722668Phase 2 · completed UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04094675Phase 2 · completed Sirolimus for Cowden Syndrome With Colon Polyposis · 230 trials list this drug (53 active) | — | — | Polyposis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01184898NA · completed Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) · 230 trials list this drug (53 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03456700Phase 2 · terminated Auranofin and Sirolimus in Treating Participants With Ovarian Cancer · 230 trials list this drug (53 active) | — | — | Ovarian Serous Tumor,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01184885early Phase 1 · completed A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Lymphoblastic Lymphoma,Adult T-Cell Leukemia/Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06957379Phase 2 · active not recruiting Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard Therapy · 230 trials list this drug (53 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01822015early Phase 1 · completed Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · 230 trials list this drug (53 active) | — | — | Adult Acute Megakaryoblastic Leukemia,Adult Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia with Maturation+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04339062Phase 1/Phase 2 · completed Cemiplimab in AlloSCT/SOT Recipients With CSCC · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm,Skin Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06941142Phase 1 · not yet recruiting A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer · 230 trials list this drug (53 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06929325Phase 3 · not yet recruiting Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 Inhibitors · 230 trials list this drug (53 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01163357Phase 1 · completed Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma,Plasma Cell Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02584647Phase 1/Phase 2 · terminated PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors · 230 trials list this drug (53 active) | — | — | Sarcoma,Malignant Peripheral Nerve Sheath Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00866684Phase 4 · terminated Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol · 230 trials list this drug (53 active) | — | — | Malignant Skin Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06856200NA · recruiting A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02432560recruiting Safety and Durability of Sirolimus for Treatment of LAM · 230 trials list this drug (53 active) | — | — | Lymphangioleiomyomatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03150914Phase 3 · active not recruiting Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial · 230 trials list this drug (53 active) | — | — | Lymphangioleiomyomatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03095703Phase 2 · completed Sirolimus and Familial Adenomatous Polyposis (FAP) · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03225417Phase 1/Phase 2 · unknown Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease. · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04348292Phase 1 · terminated Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer · 230 trials list this drug (53 active) | — | — | Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04393454Phase 2 · terminated Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06080165Phase 1/Phase 2 · withdrawn Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01428973Phase 2 · unknown Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06279494Phase 1/Phase 2 · unknown Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878524Phase 1 · terminated Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphatic System Neoplasm,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00235560Phase 2 · completed Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients · 230 trials list this drug (53 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00577278Phase 2 · completed A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04987463Phase 2/Phase 3 · unknown Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06236022Phase 4 · recruiting The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05324384Phase 2 · unknown Different Doses of Sirolimus for the Maintenance Treatment of Kaposiform Hemangioendothelioma · 230 trials list this drug (53 active) | — | — | Hemangioendothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06160739unknown Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations · 230 trials list this drug (53 active) | — | — | Lymphangioma Circumscriptum | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02642094Phase 2 · terminated Aging Mammary Stem Cells and Breast Cancer Prevention · 230 trials list this drug (53 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00414648Phase 3 · completed Efficacy and Safety of Sirolimus in LAM · 230 trials list this drug (53 active) | — | — | Lymphangioleiomyomatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04448873Phase 4 · completed Guided Discontinuation Versus Maintenance Treatment of Sirolimus in Pediatric Patients With Kaposiform Hemangioendothelioma · 230 trials list this drug (53 active) | — | — | Kaposiform Hemangioendothelioma,Hemangiomatosis with Thrombocytopenia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02110069Phase 2 · terminated A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors · 230 trials list this drug (53 active) | — | — | Kaposiform Hemangioendothelioma,Hemangiomatosis with Thrombocytopenia,Tufted Hemangioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03826628Phase 2/Phase 3 · completed Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01265030Phase 1/Phase 2 · completed A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis · 230 trials list this drug (53 active) | — | — | Desmoid Fibromatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01027000Phase 2 · completed Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03217669Phase 1 · unknown Epacadostat (INCB24360) in Combination With Sirolimus in Advanced Malignancy · 230 trials list this drug (53 active) | — | — | Solid Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03253913Phase 2 · completed Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial · 230 trials list this drug (53 active) | — | — | Lymphangioleiomyomatosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04077515Phase 4 · completed Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma · 230 trials list this drug (53 active) | — | — | Hemangioma,Kaposiform Hemangioendothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00995059Phase 1/Phase 2 · withdrawn Bortezomib Before Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00406393Phase 3 · completed Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402) · 230 trials list this drug (53 active) | — | — | Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05625919Phase 1/Phase 2 · unknown A Study of Safety and Efficacy of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa) · 230 trials list this drug (53 active) | — | — | PEComa | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05508620Phase 1 · unknown A Study of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Solid Tumors · 230 trials list this drug (53 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02688881Phase 4 · completed Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors · 230 trials list this drug (53 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00126672Phase 2 · completed RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS · 230 trials list this drug (53 active) | — | — | Kidney Angiomyolipoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03188068Phase 2 · completed Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma · 230 trials list this drug (53 active) | — | — | Kaposiform Hemangioendothelioma,Hemangiomatosis with Thrombocytopenia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05125523Phase 1 · unknown A Study of Sirolimus for Injection (Albumin Bound) in Patients With Advanced Solid Tumors · 230 trials list this drug (53 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02756572Phase 2 · completed Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms · 230 trials list this drug (53 active) | — | — | Myeloid Neoplasm,High Grade Malignant Neoplasm,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03047980Phase 2/Phase 3 · completed Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02565901Phase 1/Phase 2 · terminated Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer · 230 trials list this drug (53 active) | — | — | Malignant Prostate Neoplasm,Prostate Carcinoma,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00350181Phase 2 · completed Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT · 230 trials list this drug (53 active) | — | — | Leukemia,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03018223Phase 1 · completed Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT · 230 trials list this drug (53 active) | — | — | Acute Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02596828Phase 2 · completed Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma · 230 trials list this drug (53 active) | — | — | Pineoblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02048384Phase 1 · completed A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer · 230 trials list this drug (53 active) | — | — | Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01929642Phase 2 · completed Rapalogues for Autism Phenotype in TSC: A Feasibility Study · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02753309early Phase 1 · completed A Study of Rapamycin Combined With Intravesical BCG in Patients With Non-muscle Invasive Bladder Cancer · 230 trials list this drug (53 active) | — | — | Malignant Bladder Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01266057Phase 1 · completed Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04736589Phase 3 · not yet recruiting Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway · 230 trials list this drug (53 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02423915Phase 1 · completed Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00305682Phase 2 · completed Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Myelodysplastic Syndrome+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01526356Phase 2 · completed Topical Rapamycin to Erase Angiofibromas in TSC · 230 trials list this drug (53 active) | — | — | Angiofibroma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01467986Phase 2 · completed Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma · 230 trials list this drug (53 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00506948Phase 2 · terminated Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD) · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Leukemia,Lymphoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01658007early Phase 1 · terminated Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/Lymphoma · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Lymphoblastic Lymphoma,Adult Lymphoblastic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00047073Phase 1/Phase 2 · completed Sirolimus in Treating Patients With Glioblastoma Multiforme · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01331135Phase 1 · completed Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors · 230 trials list this drug (53 active) | — | — | Germ Cell Tumor,Hepatoblastoma,Rhabdoid Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01383668Phase 1 · withdrawn Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer · 230 trials list this drug (53 active) | — | — | Adult Solid Neoplasm,Lung Non-Small Cell Carcinoma,Lung Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01536054Phase 1 · completed Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer · 230 trials list this drug (53 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01251575Phase 2 · completed Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Childhood Myelodysplastic Syndrome,Hodgkin Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00923273Phase 1/Phase 2 · terminated Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer · 230 trials list this drug (53 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00105001Phase 2 · completed Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer · 230 trials list this drug (53 active) | — | — | Childhood Myelodysplastic Syndrome,Multiple Myeloma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01379209Phase 1/Phase 2 · completed Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT) · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00382109Phase 3 · completed Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission · 230 trials list this drug (53 active) | — | — | Childhood Acute Lymphoblastic Leukemia,Childhood B Acute Lymphoblastic Leukemia,Childhood T Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03298958Phase 3 · withdrawn Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder Cancer · 230 trials list this drug (53 active) | — | — | Malignant Bladder Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02008877Phase 1/Phase 2 · completed SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) · 230 trials list this drug (53 active) | — | — | Sarcoma,Malignant Peripheral Nerve Sheath Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01791088Phase 1 · completed Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery · 230 trials list this drug (53 active) | — | — | Adult Solid Neoplasm,Childhood Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02145559Phase 1 · completed A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors · 230 trials list this drug (53 active) | — | — | Breast Neoplasm,Lung Neoplasm,Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01537107Phase 1 · completed Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery · 230 trials list this drug (53 active) | — | — | Adult Solid Neoplasm,Malignant Pancreatic Neoplasm,Pancreatic Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01116232Phase 2 · terminated Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00409994Phase 1/Phase 2 · completed Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer · 230 trials list this drug (53 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01962896Phase 2 · terminated A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00311623Phase 1/Phase 2 · completed Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer · 230 trials list this drug (53 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00928018Phase 3 · completed Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma · 230 trials list this drug (53 active) | — | — | Hodgkin Lymphoma,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03781050Phase 4 · unknown Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01303965Phase 1/Phase 2 · terminated Allo Transplant Followed by Lenalidomide and Sirolimus Maintenance in High-Risk Multiple Myeloma (MM) · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03531281Phase 1 · withdrawn Human Lysozyme Goat Milk in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01764607Phase 2 · terminated Sirolimus in Kidney Transplant Patients With Squamous Cell Skin Carcinoma · 230 trials list this drug (53 active) | — | — | Skin Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00276744Phase 2 · terminated Individualized Drug Treatment for Treating Patients With Pancreatic Cancer · 230 trials list this drug (53 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02728700Phase 1 · terminated Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT · 230 trials list this drug (53 active) | — | — | Childhood Myelodysplastic Syndrome,Non-Hodgkin Lymphoma,Adult Acute Lymphoblastic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03662412Phase 1/Phase 2 · unknown Study of Sirolimus in Patients With Advanced Pancreatic Cancer · 230 trials list this drug (53 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02833506Phase 1 · withdrawn Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · 230 trials list this drug (53 active) | — | — | Primary Peritoneal Carcinoma,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03500367Phase 4 · unknown Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis · 230 trials list this drug (53 active) | — | — | Uterine Corpus Leiomyoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03500848Phase 2/Phase 3 · unknown Sirolimus-based Immunosuppression Treatment Regimen for Liver Transplantation · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02449564NA · completed The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid Tumors · 230 trials list this drug (53 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01195922Phase 1/Phase 2 · completed Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma · 230 trials list this drug (53 active) | — | — | Head and Neck Neoplasm,Oral Cavity Neoplasm,Squamous Cell Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00602693Phase 1 · completed T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00634270Phase 2 · completed A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01938573Phase 1/Phase 2 · completed Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer · 230 trials list this drug (53 active) | — | — | Malignant Bladder Neoplasm,Bladder Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00923845Phase 2 · completed Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer · 230 trials list this drug (53 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01689987Phase 1 · completed Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01220297Phase 2 · terminated Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT · 230 trials list this drug (53 active) | — | — | Leukemia,Hodgkin Lymphoma,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00043979Phase 2 · completed Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas · 230 trials list this drug (53 active) | — | — | Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00513474Phase 1 · completed Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01797315Phase 4 · terminated Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03140449Phase 3 · completed Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01534143Phase 2 · terminated High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant · 230 trials list this drug (53 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01181271Phase 2 · completed Tandem Auto-Allo Transplant for Lymphoma · 230 trials list this drug (53 active) | — | — | Lymphoma,Hodgkin Lymphoma,Chronic Lymphocytic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00874562Phase 1 · completed Rapamycin in Relapsed Acute Lymphoblastic Leukemia · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00499486Phase 2 · completed Sirolimus in Treating Patients With Advanced Pancreatic Cancer · 230 trials list this drug (53 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01522820Phase 1 · completed Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors · 230 trials list this drug (53 active) | — | — | Malignant Breast Neoplasm,Melanoma,Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00433485Phase 1 · completed Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00411788Phase 2 · completed A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer · 230 trials list this drug (53 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02528877Phase 1 · withdrawn Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis · 230 trials list this drug (53 active) | — | — | Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia,Primary Myelofibrosis+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02126527Phase 1 · withdrawn Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung Cancer · 230 trials list this drug (53 active) | — | — | Adult Solid Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01853423Phase 1 · completed Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00133367Phase 2 · completed Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus · 230 trials list this drug (53 active) | — | — | Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01374750Phase 2 · completed Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC) · 230 trials list this drug (53 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02724332Phase 1 · completed Adjuvant Anti-Recurrence Treatment With Rapamycin on Early-stage HCC · 230 trials list this drug (53 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00940381Phase 1 · completed Sirolimus and Cetuximab in Advanced Malignancies · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01087983Phase 1 · completed Lapatinib With Sirolimus or Metformin · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00993499Phase 1 · completed Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or Gefitinib · 230 trials list this drug (53 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01054313Phase 1 · completed Docetaxel and Sirolimus in Patients With Advanced Malignancies · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00971789Phase 2 · completed Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00634244Phase 2 · completed Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia · 230 trials list this drug (53 active) | — | — | Adult Acute Megakaryoblastic Leukemia,Adult Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia with Maturation+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01827618early Phase 1 · completed Neoadjuvant Rapamycin in Patients Undergoing Radical Cystectomy · 230 trials list this drug (53 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00821080Phase 1 · completed Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma · 230 trials list this drug (53 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01488253Phase 2 · terminated Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants · 230 trials list this drug (53 active) | — | — | Leukemia,Acute Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00068302Phase 1 · terminated Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia or Non-Hodgkin's Lymphoma · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00002790Phase 1/Phase 2 · withdrawn Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant · 230 trials list this drug (53 active) | — | — | Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00589563Phase 2 · completed Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer · 230 trials list this drug (53 active) | — | — | Leukemia,Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00450320Phase 1 · completed Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma · 230 trials list this drug (53 active) | — | — | Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00355862Phase 3 · completed Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma · 230 trials list this drug (53 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00353301Phase 2 · completed Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma · 230 trials list this drug (53 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00375245Phase 1 · completed Rapamycin With Grapefruit Juice for Advanced Malignancies · 230 trials list this drug (53 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00667485Phase 1 · completed Rapamycin Plus Bevacizumab in Advanced Cancers · 230 trials list this drug (53 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |