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Acute Leukemia · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Leukemia
Acute Leukemia

Hematologic Malignancy

Acute Leukemia

CI-CAN-00000399Explore in graph →

Hematologic1,260 active trials30 approved drugs323 evidence items

NCIt: C9300
DOID: 12603

Overview
Statistics
Survival
Genomics17
Variants & evidence323
Drugs53
Trials4653
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A clonal (malignant) hematopoietic disorder with an acute onset, affecting the bone marrow and the peripheral blood. The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts).

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

LeukemiaCancer Family

Children (5)

ncit

Acute Leukemia of Ambiguous Lineage10 sub
Acute Lymphoblastic Leukemia6 sub
Acute Myeloid Leukemia13 sub
Burkitt Leukemia2 sub
Childhood Acute Leukemia4 sub

273 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

Hematopoietic and Lymphatic SystemC35813

Record

Identity

CancerIndex ID: CI-CAN-00000399
Entity type: Hematologic Malignancy
Malignant: Yes
Solid / hematologic: Hematologic
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

4,653 / 1,260

Publications (all / 5y)

20,477 / 3,371

Evidence items

323

Genes / variants

217 / 100

Drugs (any / approved)

53 / 30

Genomic cohorts

17

Epidemiology / survival obs.

0 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (1)

Acute Leukemiasynonym · CIViC

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths23,740countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #7 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
US new cases58,254countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #11 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
US age-standardized mortality5.5per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #6 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
Active trials1,260countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #34 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials760countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #33 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items323countaccepted CIViC items · entity + descendantscivicComputedrank #21 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months679countPubMed records · stored query · 12-month windowpubmedComputedrank #122 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts17countopen GDC projects · entity + descendantsgdcComputedrank #82 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants