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Soft Tissue Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Connective and Soft Tissue Neoplasm
Soft Tissue Neoplasm

Cancer Family

Soft Tissue Neoplasm

CI-CAN-00000354Explore in graph →

Non-malignant441 active trials9 approved drugs183 evidence items

NCIt: C3377
MeSH: D012983

Overview
Statistics
Survival
Genomics6
Variants & evidence183
Drugs14
Trials2078
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

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Trials tab
Methodology: publication counts

Literature

Linked publications (107)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 26–50 of 107 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridization assays.
· Hum Pathol · 2008 · PMID 17950782 · validated civic_curation pubmed
Prognostic value of CTNNB1 gene mutation in primary sporadic aggressive fibromatosis.
· Ann Surg Oncol · 2015 · PMID 25341748 · validated civic_curation pubmed
The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25.
· Oncogene · 2001 · PMID 11244503 · validated civic_curation pubmed
Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney.
· Nat Genet · 2015 · PMID 26098867 · validated civic_curation pubmed
Technique for differentiating alveolar soft part sarcoma from other tumors in paraffin-embedded tissue: comparison of immunohistochemistry for TFE3 and CD147 and of reverse transcription polymerase chain reaction for ASPSCR1-TFE3 fusion transcript.
· Hum Pathol · 2012 · PMID 21835426 · validated civic_curation pubmed
TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers.
· Am J Surg Pathol · 2016 · PMID 26975036 · validated civic_curation pubmed
Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG).

Showing 26–50 of 107 publications

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· Neuro Oncol · 2022 · PMID 35395680 · validated civic_curation pubmed

Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma.

· Mod Pathol · 2007 · PMID 17334349 · validated civic_curation pubmed

Identification of t(17;22)(q22;q13) (COL1A1/PDGFB) in dermatofibrosarcoma protuberans by fluorescence in situ hybridization in paraffin-embedded tissue microarrays.

· Hum Pathol · 2011 · PMID 21111450 · validated civic_curation pubmed

Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma.

· Mod Pathol · 2019 · PMID 30459475 · validated civic_curation pubmed

A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential.

· Lab Invest · 2004 · PMID 15146165 · validated civic_curation pubmed

Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate.

· Clin Cancer Res · 2006 · PMID 16551858 · validated civic_curation pubmed

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.

· Clin Cancer Res · 2006 · PMID 16638875 · validated civic_curation pubmed

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size.

· Am J Pathol · 2002 · PMID 12000708 · validated civic_curation pubmed

Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors.

· Cancer Res · 1999 · PMID 10485475 · validated civic_curation pubmed

SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.

· N Engl J Med · 1998 · PMID 9428816 · validated civic_curation pubmed

The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study.

· BMC Cancer · 2012 · PMID 22439647 · validated civic_curation pubmed

Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor.

· J Clin Oncol · 2008 · PMID 18955458 · validated civic_curation pubmed

Molecular genetic characterization of the genomic ACTB-GLI fusion in pericytoma with t(7;12).

· Biochem Biophys Res Commun · 2004 · PMID 15555571 · validated civic_curation pubmed

Long-term follow-up results of the multicenter phase II trial of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of standard tyrosine kinase inhibitor therapy.

· Ann Oncol · 2016 · PMID 27371698 · validated civic_curation pubmed

Recurrent NTRK1 Gene Fusions Define a Novel Subset of Locally Aggressive Lipofibromatosis-like Neural Tumors.

· Am J Surg Pathol · 2016 · PMID 27259011 · validated civic_curation pubmed

Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions.

· Mod Pathol · 2013 · PMID 23060122 · validated civic_curation pubmed

Detection of COL1A1-PDGFB fusion transcripts and PDGFB/PDGFRB mRNA expression in dermatofibrosarcoma protuberans.

· Mod Pathol · 2007 · PMID 17431412 · validated civic_curation pubmed

Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney.

· Oncotarget · 2015 · PMID 26516930 · validated civic_curation pubmed

Exploring the Histogenesis and Diagnostic Strategy Using Immunoassay and RT-PCR in Alveolar Soft Part Sarcoma.

· Pathol Oncol Res · 2018 · PMID 28766250 · validated civic_curation pubmed