Publication
Prognostic value of CTNNB1 gene mutation in primary sporadic aggressive fibromatosis.
Authors not recorded
Ann Surg Oncol2015PMID 25341748stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerDesmoid Fibromatosiscivic_curation1.00
- geneCTNNB1civic_curation1.00
- variantCTNNB1 S45Fcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25341748
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CTNNB1 S45F1 | ||||||||
| (prognostic) | Desmoid FibromatosisALIAS | Prognostic | B | Supports Poor Outcome | 4 | accepted | EID9788This was a multi-institutional retrospective cohort study which looked at the prognostic value of CTNNB1 gene mutations in aggressive fibromatosis (also known as desmoid tumor). The study analyzed 101… (full text at CIViC) PMID 25341748 · van Broekhoven et al., 2015 · Open in CIViC | civic |