Publication
Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
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Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerEpithelioid Sarcomacivic_curation1.00
- cancerRhabdoid Tumorcivic_curation1.00
- geneSMARCB1civic_curation1.00
- variantSMARCB1 Losscivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 23060122
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| SMARCB1 Loss2 | ||||||||
| (oncogenic) | Epithelioid Sarcoma | Oncogenic | B | Supports Oncogenicity | 3 | accepted | EID9993This study aimed to characterize the spectrum of SMARCB1 gene abnormalities in epithelioid sarcoma. 19/21 patients were SMARCB1 immunohistochemistry-negative. Multiplex ligation dependent probe amplif… (full text at CIViC) PMID 23060122 · Sullivan et al., 2013 · Open in CIViC | civic |
| (diagnostic) | Rhabdoid TumorALIAS | Diagnostic | B | Does Not Support Positive | 2 | accepted | EID11090The authors characterized the occurrence of SMARCB1 gene loss in epithelioid sarcomas. SMARCB1 immunohistochemistry staining demonstrated 19/21 patient samples were negative. Multiplex ligation depend… (full text at CIViC) PMID 23060122 · Sullivan et al., 2013 · Open in CIViC | civic |