Publication
Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma.
Authors not recorded
Mod Pathol2019PMID 30459475PMC6486453stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerPseudomyogenic Hemangioendotheliomacivic_curation1.00
- geneFOSBcivic_curation1.00
- variantFOSB Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 30459475
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| FOSB Fusion1 | ||||||||
| (diagnostic) | Pseudomyogenic Hemangioendothelioma | Diagnostic | B | Supports Positive | 4 | accepted | EID12779In this 2019 study, targeted RNA sequencing using the Archer FusionPlex technology was validated and implemented to detect oncogenic fusion transcripts in 62 genes recurrently rearranged in solid tumo… (full text at CIViC) PMID 30459475 · Zhu et al., 2019 · Open in CIViC | civic |