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Hematopoietic and Lymphoid Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Hematopoietic and Lymphoid Cell Neoplasm

Cancer Family

Hematopoietic and Lymphoid Cell Neoplasm

CI-CAN-00000023Explore in graph →

HematologicNon-malignant4,231 active trials98 approved drugs1,009 evidence items

NCIt: C27134
DOID: 2531
MeSH: D019337

Overview
Statistics
Survival
Genomics60
Variants & evidence1009
Drugs99
Trials18680
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (735)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 451–475 of 735 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus.
· Nature · 1990 · PMID 2170850 · validated civic_curation pubmed
Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.
· J Exp Med · 1990 · PMID 2175343 · validated civic_curation pubmed
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.
· Blood · 1995 · PMID 7780150 · validated civic_curation pubmed
TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.
· Leukemia · 1995 · PMID 8609706 · validated civic_curation pubmed
Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study.
· Blood · 2016 · PMID 27114462 · validated civic_curation pubmed
NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report.
· Blood · 2014 · PMID 25145343 · validated civic_curation pubmed
Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia.
· Haematologica · 2023 · PMID 36815378 · validated civic_curation

Showing 451–475 of 735 publications

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B acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease.

· Mod Pathol · 2014 · PMID 24030742 · validated civic_curation pubmed

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.

· Cancer Cell · 2016 · PMID 26859458 · validated civic_curation pubmed

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

· Nat Med · 2018 · PMID 29227476 · validated civic_curation pubmed

Optimized cytogenetic risk-group stratification of KMT2A-rearranged pediatric acute myeloid leukemia.

· Blood Adv · 2024 · PMID 38621200 · validated civic_curation pubmed

The KMT2A recombinome of acute leukemias in 2023.

· Leukemia · 2023 · PMID 37019990 · validated civic_curation pubmed

The MLL recombinome of acute leukemias in 2017.

· Leukemia · 2018 · PMID 28701730 · validated civic_curation pubmed

Multilineage involvement in KMT2A-rearranged B acute lymphoblastic leukaemia: cell-of-origin, biology, and clinical implications.

· Histopathology · 2024 · PMID 38686611 · validated civic_curation pubmed

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.

· N Engl J Med · 2005 · PMID 15659725 · validated civic_curation pubmed

Cryptic BCR-ABL fusion gene as variant rearrangement in chronic myeloid leukemia: molecular cytogenetic characterization and influence on TKIs therapy.

· Oncotarget · 2017 · PMID 28404889 · validated civic_curation pubmed

Molecular cytogenetic characterization of variant Philadelphia translocations in chronic myeloid leukemia: genesis and deletion of derivative chromosome 9.

· Cancer Genet Cytogenet · 2009 · PMID 19737651 · validated civic_curation pubmed

PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.

· Leukemia · 2025 · PMID 39702796 · validated civic_curation pubmed

RAS mutations in early age leukaemia modulated by NQO1 rs1800566 (C609T) are associated with second-hand smoking exposures.

· BMC Cancer · 2014 · PMID 24571676 · validated civic_curation pubmed

Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).

· Blood · 2013 · PMID 23632886 · validated civic_curation pubmed

RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years.

· Blood · 2005 · PMID 15951308 · validated civic_curation pubmed

Implications of NRAS mutations in AML: a study of 2502 patients.

· Blood · 2006 · PMID 16434492 · validated civic_curation pubmed

Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B.

· Haematologica · 2009 · PMID 19059939 · validated civic_curation pubmed

The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA.

· Blood · 2010 · PMID 19965647 · validated civic_curation pubmed

Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party.

· J Clin Oncol · 2008 · PMID 18591546 · validated civic_curation pubmed