Publication
Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerB Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likecivic_curation1.00
- geneEPORcivic_curation1.00
- variantEPOR rearrangementscivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26859458
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| EPOR rearrangements1 | ||||||||
| (diagnostic) | B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like | Diagnostic | B | Supports Positive | 4 | accepted | EID12397This 2017 study is result of collaboration of multiple institutions and was led by St. Jude Children's Research Hospital team. The total cohort of 3115 B-ALL patients (all ages) was studied, with 212 … (full text at CIViC) PMID 26859458 · Iacobucci et al., 2016 · Open in CIViC | civic |
| EPOR Overexpression1 | ||||||||
| Inhibitor | Childhood B-cell Acute Lymphoblastic LeukemiaUNRESOLVED | Predictive | D | Supports Sensitivity Response | 3 | submitted | EID7206EPOR overexpression in B-ALL is associated with the Philadelphia-like subtype of the disease (although high EPOR expression can also be observed in B-ALL with t(12;21)-ETV6-RUNX1). In this study, EPO… (full text at CIViC) PMID 26859458 · Iacobucci et al., 2016 · Open in CIViC | civic |