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Hematopoietic and Lymphoid Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Hematopoietic and Lymphoid Cell Neoplasm

Cancer Family

Hematopoietic and Lymphoid Cell Neoplasm

CI-CAN-00000023Explore in graph →

HematologicNon-malignant4,231 active trials98 approved drugs1,009 evidence items

NCIt: C27134
DOID: 2531
MeSH: D019337

Overview
Statistics
Survival
Genomics60
Variants & evidence1009
Drugs99
Trials18680
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (735)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 426–450 of 735 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias.
· Blood · 1991 · PMID 1671560 · validated civic_curation pubmed
Immunologic, cytogenetic, and clinical characterization of childhood acute lymphoblastic leukemia with the t(1;19) (q23; p13) or its derivative.
· J Clin Oncol · 1994 · PMID 7989935 · validated civic_curation pubmed
Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
· Nat Genet · 2017 · PMID 28112737 · validated civic_curation pubmed
Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes.
· J Clin Oncol · 2021 · PMID 33449813 · validated civic_curation pubmed
Philadelphia chromosome-positive acute myeloid leukemia: a rare aggressive leukemia with clinicopathologic features distinct from chronic myeloid leukemia in myeloid blast crisis.
· Am J Clin Pathol · 2007 · PMID 17369142 · validated civic_curation pubmed
Philadelphia chromosome-positive acute myeloid leukemia: cytoimmunologic and cytogenetic features.
· Haematologica · 1996 · PMID 8952155 · validated civic_curation pubmed
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.

Showing 426–450 of 735 publications

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· Blood · 2010 · PMID 20385793 · validated civic_curation pubmed

Poor treatment outcome of Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia despite intensive chemotherapy.

· Leuk Lymphoma · 1999 · PMID 10194126 · validated civic_curation pubmed

Translocation (9;22) is associated with extremely poor prognosis in intensively treated children with acute lymphoblastic leukemia.

· Blood · 1991 · PMID 1991160 · validated civic_curation pubmed

The genomic landscape of pediatric acute lymphoblastic leukemia.

· Nat Genet · 2022 · PMID 36050548 · validated civic_curation pubmed

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

· Blood · 2013 · PMID 23974201 · validated civic_curation pubmed

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome.

· Blood · 2022 · PMID 34320176 · validated civic_curation pubmed

Prognostic impact of CEBPA bZIP domain mutation in acute myeloid leukemia.

· Blood Adv · 2022 · PMID 34448807 · validated civic_curation pubmed

CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group.

· Blood · 2021 · PMID 33951732 · validated civic_curation pubmed

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

· Nat Genet · 2016 · PMID 27019113 · validated civic_curation pubmed

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.

· Nat Genet · 2016 · PMID 27776115 · validated cbioportal_study pubmed

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.

· Nat Commun · 2016 · PMID 27265895 · validated civic_curation pubmed

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.

· Blood · 2011 · PMID 21487109 · validated civic_curation pubmed

Distinct molecular profile of IRF4-rearranged large B-cell lymphoma.

· Blood · 2020 · PMID 31738823 · validated civic_curation pubmed

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.

· Cancer Cell · 2012 · PMID 22897847 · validated civic_curation pubmed

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

· Nat Genet · 2001 · PMID 11431691 · validated civic_curation pubmed

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study.

· Blood · 2015 · PMID 26215111 · validated civic_curation pubmed

Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Study Group.

· Blood · 1997 · PMID 9226156 · validated civic_curation pubmed

Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.

· Blood · 1997 · PMID 9242552 · validated civic_curation pubmed

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group.

· Blood · 2018 · PMID 30150206 · validated civic_curation pubmed