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Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia.

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Haematologica2023PMID 36815378PMC10388277stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

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Linked entities

Linked entities (3)

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Validated 3

Curated evidence

Evidence citing this paper (1)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
36815378
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
NUP98 Fusion1
(diagnostic)Acute Myeloid Leukemia with NUP98 RearrangementDiagnosticBSupports Positive4accepted
EID12380

In this 2023 study the authors included 2,235 children and young adults diagnosed with acute myeloid leukemia (AML). NUP98 fusions were detected in these patients either by karyotype of RNA sequencing… (full text at CIViC)

PMID 36815378 · Bertrums et al., 2023 · Open in CIViC

civic