Publication
B acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Data not yet available
Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerB Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likecivic_curation1.00
- geneEPORcivic_curation1.00
- variantEPOR Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24030742
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| EPOR Fusion1 | ||||||||
| (diagnostic) | B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like | Diagnostic | B | Supports Positive | 4 | accepted | EID12395This MD Anderson Cancer Center study describes six adult patients (3 males and 3 females, median age 39 yo) with t(14;19)(q32;p13) resulting in IGH::EPOR. 3 patients did not receive any prior chemothe… (full text at CIViC) PMID 24030742 · Jaso et al., 2014 · Open in CIViC | civic |
| EPOR Overexpression1 | ||||||||
| (prognostic) | Childhood B-cell Acute Lymphoblastic LeukemiaUNRESOLVED | Prognostic | C | Supports Poor Outcome | 3 | submitted | EID7205The manuscripts describes a small case series (6 patients) with the t(14;19)(q32;p13.1) involving the EPOR locus in 19p13.1 and the IGH locus in 14q32, which is predicted to result in EPOR overexpress… (full text at CIViC) PMID 24030742 · Jaso et al., 2014 · Open in CIViC | civic |