Subtype
Colorectal Carcinoma
CI-CAN-00005005CRCExplore in graph →
344 active trials5 approved drugs22 evidence items
- NCIt
- C2955
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Subtype
CI-CAN-00005005CRCExplore in graph →
Clinical trials
1,010 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (127)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02935309 | Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma | completed | Phase 1 | 20 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | May 31, 2022 | clinicaltrials |
| NCT05388513 | Evaluating Factors Affecting Survival in Colon and Rectum Cancer | completed | — | 161 | Umraniye Education and Research HospitalOTHER_GOV | 0 | May 24, 2022 | clinicaltrials |
| NCT04443985 | A Cohort of Predictive Factor of Pathologic Complete Response After Preoperative Neoadjuvant in Rectum Cancer | completed | — | 140 | Mahidol UniversityOTHER | 1 | May 20, 2022 | clinicaltrials |
| NCT05382377 | NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors | unknown | Early Phase 1 | 18 | jianming xuOTHER | 1 | May 19, 2022 | clinicaltrials |
| NCT05154474 | Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy(SPACE2) | unknown | — | 150 | WepromOTHER | 1 | May 3, 2022 | clinicaltrials |
| NCT05239650 | Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07+HLX10 +mFOLFOX6 or HLX07 Monotherapy in Patients With mCRC | not yet recruiting | Phase 2 | 50 | Shanghai Henlius BiotechINDUSTRY | 0 | May 3, 2022 | clinicaltrials |
| NCT05317351 | A Prospective Randomized Study Comparing the Adenoma Detection Yield of SC, AI and Combined AI and G-EYE® | unknown | N/A | 2,160 | Smart Medical Systems Ltd.INDUSTRY | 1 | Apr 7, 2022 | clinicaltrials |
| NCT02817126 | Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer(REAL) | unknown | N/A | 1,240 | Fudan UniversityOTHER | 1 | Mar 22, 2022 | clinicaltrials |
| NCT05287165 | Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms | unknown | Early Phase 1 | 19 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Mar 18, 2022 | clinicaltrials |
| NCT03403634 | Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver | completed | Phase 2 | 19 | Roswell Park Cancer InstituteOTHER | 1 | Mar 2, 2022 | clinicaltrials |
| NCT03688906 | AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test | completed | — | 3,275 | Freenome Holdings Inc.INDUSTRY | 2 | Mar 2, 2022 | clinicaltrials |
| NCT03875313 | Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors | terminated | Phase 1 / Phase 2 | 33 | Calithera Biosciences, IncINDUSTRY | 1 | Feb 17, 2022 | clinicaltrials |
| NCT02178722 | Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers | completed | Phase 1 / Phase 2 | 444 | Incyte CorporationINDUSTRY | 1 | Feb 14, 2022 | clinicaltrials |
| NCT02248805 | Phase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal Carcinoma | completed | Phase 1 | 95 | MacroGenicsINDUSTRY | 1 | Feb 8, 2022 | clinicaltrials |
| NCT04119830 | Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer | withdrawn | Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | Feb 8, 2022 | clinicaltrials |
| NCT05201872 | Bacteriological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. | unknown | — | 216 | Yanhong DengOTHER | 1 | Feb 7, 2022 | clinicaltrials |
| NCT05201885 | Oncological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. | unknown | — | 192 | Yanhong DengOTHER | 1 | Feb 3, 2022 | clinicaltrials |
| NCT04790227 | MRI for Selection of Complete Responders After Chemoradiation for Locally Advanced Rectal Cancer | unknown | — | 50 | Assiut UniversityOTHER | 1 | Feb 1, 2022 | clinicaltrials |
| NCT02292758 | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery | completed | Phase 2 | 36 | Academic and Community Cancer Research UnitedOTHER | 1 | Jan 31, 2022 | clinicaltrials |
| NCT01285102 | Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer | terminated | Phase 1 | 4 | Fox Chase Cancer CenterOTHER | 1 | Dec 20, 2021 | clinicaltrials |
| NCT03050814 | Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004 | terminated | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 20, 2021 | clinicaltrials |
| NCT05162248 | Microsatellite Instability in Colorectal Cancers(MSI-CRC) | completed | — | 231 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, TurkeyOTHER | 1 | Dec 17, 2021 | clinicaltrials |
| NCT04078828 | PR in Endoscopic LAR for Rectal Cancer | unknown | N/A | 10 | Southwest Hospital, ChinaOTHER | 1 | Nov 30, 2021 | clinicaltrials |
| NCT03949777 | Validation of Aer-O-Scope Colonoscope System Cecal Intubation | completed | N/A | 79 | GI View Ltd.INDUSTRY | 1 | Nov 18, 2021 | clinicaltrials |
| NCT05116696 | Comparison of Outcomes of Patients With Stage IV Chronic Limb-threatening Ischemia and Colorectal Cancer | completed | — | 836 | Clinical Centre of SerbiaOTHER | 1 | Nov 11, 2021 | clinicaltrials |
| NCT04418895 | Neoadjuvant Therapy for Localized Rectal Adenocarcinoma | withdrawn | Phase 2 | 0 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Nov 10, 2021 | clinicaltrials |
| NCT02319304 | Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma(GCC 1314) | terminated | Phase 2 | 3 | University of Maryland, BaltimoreOTHER | 1 | Nov 4, 2021 | clinicaltrials |
| NCT04831827 | Promoting Equity for Cancer Screening and Follow-up | withdrawn | N/A | 0 | Mayo ClinicOTHER | 1 | Oct 27, 2021 | clinicaltrials |
| NCT04582981 | Fruquintinib and Raltitrexed Versus Fruquintinib Monotherapy in Advanced Colorectal Cancer | unknown | Phase 2 | 136 | Fudan UniversityOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT05080088 | Retrospective Evaluation of 3 Colonic Adenoma Detection Strategies(COLODETECT) | completed | — | 90 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Oct 15, 2021 | clinicaltrials |
| NCT05077358 | Intracorporeal Versus Extracorporeal Anastomosis In Laparoscopic Right Colon Resection | unknown | N/A | 241 | Yonsei UniversityOTHER | 1 | Oct 14, 2021 | clinicaltrials |
| NCT01899547 | Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum(LASRE) | unknown | N/A | 1,070 | Fujian Medical UniversityOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT04109755 | Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer(PEMREC) | recruiting | Phase 2 | 25 | University Hospital, GenevaOTHER | 1 | Sep 30, 2021 | clinicaltrials |
| NCT02347735 | Predictive Factors for Anastomotic Leakage After Colorectal Surgery(REVEAL) | completed | — | 774 | Maastricht University Medical CenterOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT04781270 | mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases | unknown | Phase 3 | 308 | Fudan UniversityOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT04069455 | ePRO for Adjuvant Therapy of Colorectal Adenocarcinoma | unknown | N/A | 270 | Zhejiang UniversityOTHER | 1 | Sep 17, 2021 | clinicaltrials |
| NCT03280277 | Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer | terminated | Early Phase 1 | 2 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT04003181 | The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon | completed | N/A | 64 | University of AarhusOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT00040599 | Safety Study of 90Y-hMN14 to Treat Colorectal Cancer | completed | Phase 1 / Phase 2 | 72 | Gilead SciencesINDUSTRY | 5 | Aug 19, 2021 | clinicaltrials |
| NCT00041652 | Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer | completed | Phase 1 / Phase 2 | 30 | Gilead SciencesINDUSTRY | 1 | Aug 19, 2021 | clinicaltrials |
| NCT04490551 | Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controlled Trial | completed | N/A | 6,753 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Aug 13, 2021 | clinicaltrials |
| NCT04607291 | Health Service Intervention for the Improvement of Access and Adherence to Colorectal Cancer Screening | completed | Phase 1 | 183 | Roswell Park Cancer InstituteOTHER | 1 | Aug 12, 2021 | clinicaltrials |
| NCT03337776 | Effect of WhatsApp Messenger on Uptake of CRC Screening Study | withdrawn | N/A | 0 | Chinese University of Hong KongOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT04988191 | Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Peking UniversityOTHER | 1 | Aug 3, 2021 | clinicaltrials |
| NCT02073500 | Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies(PSM) | recruiting | — | 300 | Oslo University HospitalOTHER | 1 | Jul 28, 2021 | clinicaltrials |
| NCT02270606 | Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer | completed | Phase 1 | 14 | Virginia Commonwealth UniversityOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT02533271 | Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer(STELLAR) | unknown | Phase 3 | 600 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT02393755 | Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 42 | Roswell Park Cancer InstituteOTHER | 1 | Jul 8, 2021 | clinicaltrials |
| NCT03142516 | FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status(OPALO) | completed | Phase 2 | 20 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT03300570 | Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers | completed | Phase 1 | 27 | National Cancer Institute (NCI)NIH | 1 | Jun 14, 2021 | clinicaltrials |
Data updated 23 days agoSource updated May 31, 2022source: clinicaltrials