Subtype
Colorectal Carcinoma
CI-CAN-00005005CRCExplore in graph →
344 active trials5 approved drugs22 evidence items
- NCIt
- C2955
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Subtype
CI-CAN-00005005CRCExplore in graph →
Clinical trials
1,010 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (127)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06349044 | A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. | unknown | N/A | 120 | Zhejiang Cancer HospitalOTHER | 1 | Aug 27, 2024 | clinicaltrials |
| NCT05867303 | A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors | unknown | Phase 1 | 48 | RemeGen Co., Ltd.INDUSTRY | 2 | Aug 16, 2024 |
| clinicaltrials |
| NCT06540027 | The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer | unknown | — | 80 | Başakşehir Çam & Sakura City HospitalOTHER_GOV | 1 | Aug 15, 2024 | clinicaltrials |
| NCT06339346 | Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection(PROMOT1) | unknown | — | 400 | University Hospital, BrestOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT06524362 | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial(PERECARE) | unknown | N/A | 77 | GEM Hospital & Research CenterOTHER | 1 | Jul 29, 2024 | clinicaltrials |
| NCT05883683 | Molecular Study and Precision Medicine for Colorectal Cancer(MSPM) | unknown | — | 100 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jul 24, 2024 | clinicaltrials |
| NCT02355379 | Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over(ADAGE) | unknown | Phase 3 | 774 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Jul 8, 2024 | clinicaltrials |
| NCT04432857 | AN0025 and Pembrolizumab Combination in Advanced Solid Tumors | unknown | Phase 1 | 63 | Adlai Nortye Biopharma Co., Ltd.INDUSTRY | 2 | Jun 27, 2024 | clinicaltrials |
| NCT06458725 | Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers(PILLAR) | unknown | N/A | 30 | Jules Bordet InstituteOTHER | 0 | Jun 14, 2024 | clinicaltrials |
| NCT03992456 | Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer | unknown | Phase 2 | 12 | Academic and Community Cancer Research UnitedOTHER | 1 | May 21, 2024 | clinicaltrials |
| NCT03337087 | Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer | unknown | Phase 1 / Phase 2 | 18 | Academic and Community Cancer Research UnitedOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT06261008 | Interactive Telehealth Intervention to Increase Longitudinal Adherence to Repeat Faecal Immunochemical Test Screening | unknown | N/A | 370 | Chinese University of Hong KongOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT04755920 | SGM-101 in Colorectal Brain Metastases.(SGM-CBM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | May 9, 2024 | clinicaltrials |
| NCT06206096 | PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC | unknown | Phase 2 | 40 | Chinese PLA General HospitalOTHER | 1 | Apr 30, 2024 | clinicaltrials |
| NCT04301557 | PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer | unknown | Phase 2 | 25 | Sun Yat-sen UniversityOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT05305820 | Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy(PANO) | unknown | N/A | 36 | Dublin City UniversityOTHER | 1 | Mar 21, 2024 | clinicaltrials |
| NCT06008522 | Safety and Feasibility of Immuno-OCT(DETOUR) | unknown | N/A | 15 | University Medical Center GroningenOTHER | 0 | Mar 20, 2024 | clinicaltrials |
| NCT06311279 | End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum | unknown | N/A | 20 | Sohag UniversityOTHER | 1 | Mar 15, 2024 | clinicaltrials |
| NCT06304597 | Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy(PREDICT) | unknown | Phase 1 | 18 | University Medical Center GroningenOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT04096417 | Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations | unknown | Phase 2 | 14 | Academic and Community Cancer Research UnitedOTHER | 1 | Feb 21, 2024 | clinicaltrials |
| NCT06262581 | Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before Surgery | unknown | Phase 2 | 40 | Sun Yat-sen UniversityOTHER | 1 | Feb 16, 2024 | clinicaltrials |
| NCT03799939 | Chimney Trial of Parastomal Hernia Prevention | unknown | N/A | 141 | University of OuluOTHER | 2 | Feb 1, 2024 | clinicaltrials |
| NCT05646043 | PREHAB - Improving Condition Before Surgery | unknown | N/A | 40 | University Hospital OstravaOTHER | 1 | Jan 18, 2024 | clinicaltrials |
| NCT06171854 | caBozantinib in Pre-treated pAtients With Metastatic COlorectal Cancer.(ABACO) | unknown | Phase 2 | 33 | University of Campania Luigi VanvitelliOTHER | 1 | Jan 2, 2024 | clinicaltrials |
| NCT06115174 | Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer(CRC - PTX) | unknown | Phase 4 | 44 | Tanta UniversityOTHER | 0 | Nov 2, 2023 | clinicaltrials |
| NCT06050447 | Factors Affecting the Results of Treatment of Patients With Colorectal Cancer | unknown | — | 1,200 | Immanuel Kant Baltic Federal UniversityOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT06017141 | Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study | unknown | Phase 2 | 80 | University of Kansas Medical CenterOTHER | 1 | Aug 30, 2023 | clinicaltrials |
| NCT04984369 | The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment | unknown | Phase 2 | 50 | Shanghai Henlius BiotechINDUSTRY | 1 | Aug 21, 2023 | clinicaltrials |
| NCT03619668 | Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment(AMPERE) | unknown | — | 16 | Aalborg University HospitalOTHER | 1 | Aug 3, 2023 | clinicaltrials |
| NCT05969938 | Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology | unknown | — | 50 | WeiWei XiaoOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05920928 | Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer(TEHRAN) | unknown | N/A | 114 | Tehran University of Medical SciencesOTHER | 0 | Jun 27, 2023 | clinicaltrials |
| NCT05247346 | Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements(SENSITIVE) | unknown | N/A | 60 | University Medical Center GroningenOTHER | 1 | Jun 13, 2023 | clinicaltrials |
| NCT05233332 | Study of HL-085 and Vemurafinib in Metastatic Colorectal Cancer (mCRC)(mCRC) | unknown | Phase 2 | 186 | Shanghai Kechow Pharma, Inc.INDUSTRY | 1 | May 31, 2023 | clinicaltrials |
| NCT05799820 | QL1706 Monotherapy or in Combination With Bevacizumab and XELOX as First-line Treatment of Unresectable Advanced or Metastatic CRC | unknown | Phase 2 | 60 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 25, 2023 | clinicaltrials |
| NCT03699761 | The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection | unknown | N/A | 1,000 | Southwest Hospital, ChinaOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05815290 | Cadonilimab in Locally Advanced MSI-H/dMMR Colorectal Cancer | unknown | Phase 2 | 50 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05245565 | Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer | unknown | — | 120 | Shanghai 10th People's HospitalOTHER | 1 | Apr 13, 2023 | clinicaltrials |
| NCT05429866 | Immunological Variables Associated to ICI Toxicity in Cancer Patients | unknown | Phase 2 | 441 | Jules Bordet InstituteOTHER | 1 | Mar 8, 2023 | clinicaltrials |
| NCT05185557 | BRIANSTORM - Early Identification of Patients With Brain Metastases | unknown | — | 50 | Aarhus University HospitalOTHER | 1 | Feb 3, 2023 | clinicaltrials |
| NCT05685680 | Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma | unknown | N/A | 50 | Sohag UniversityOTHER | 1 | Jan 17, 2023 | clinicaltrials |
| NCT05314309 | Prospective Clinical Validation of a Novel Multitarget FIT in CRC Screening(mtFIT) | unknown | — | 14,712 | The Netherlands Cancer InstituteOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT05645094 | Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer | unknown | — | 38 | Fudan UniversityOTHER | 0 | Dec 13, 2022 | clinicaltrials |
| NCT05635149 | Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal Cancer | unknown | — | 100 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT05422547 | Role of Immunoscore® in Stage II-III Colorectal Cancer | unknown | — | 100 | D'Or Institute for Research and EducationOTHER | 1 | Jun 16, 2022 | clinicaltrials |
| NCT05411783 | Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial(LOTHVEIN) | unknown | N/A | 84 | San Carlo di Nancy HospitalOTHER | 1 | Jun 9, 2022 | clinicaltrials |
| NCT05406206 | Hepatic Arterial Infusion Chemotherapy With Fruquintinib for Colorectal Cancer Liver Metastases As Third-line Therapy | unknown | Phase 2 | 27 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 6, 2022 | clinicaltrials |
| NCT05382377 | NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors | unknown | Early Phase 1 | 18 | jianming xuOTHER | 1 | May 19, 2022 | clinicaltrials |
| NCT05154474 | Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy(SPACE2) | unknown | — | 150 | WepromOTHER | 1 | May 3, 2022 | clinicaltrials |
| NCT05317351 | A Prospective Randomized Study Comparing the Adenoma Detection Yield of SC, AI and Combined AI and G-EYE® | unknown | N/A | 2,160 | Smart Medical Systems Ltd.INDUSTRY | 1 | Apr 7, 2022 | clinicaltrials |
| NCT02817126 | Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer(REAL) | unknown | N/A | 1,240 | Fudan UniversityOTHER | 1 | Mar 22, 2022 | clinicaltrials |
Data updated 22 days agoSource updated Aug 27, 2024source: clinicaltrials