Subtype
Colorectal Carcinoma
CI-CAN-00005005CRCExplore in graph →
344 active trials5 approved drugs22 evidence items
- NCIt
- C2955
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Subtype
CI-CAN-00005005CRCExplore in graph →
Clinical trials
1,010 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (127)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03699761 | The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection | unknown | N/A | 1,000 | Southwest Hospital, ChinaOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05815290 | Cadonilimab in Locally Advanced MSI-H/dMMR Colorectal Cancer | unknown | Phase 2 | 50 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05245565 | Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer | unknown | — | 120 | Shanghai 10th People's HospitalOTHER | 1 | Apr 13, 2023 | clinicaltrials |
| NCT03849469 | A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors(DUET-4) | completed | Phase 1 | 78 | Xencor, Inc.INDUSTRY | 1 | Mar 30, 2023 | clinicaltrials |
| NCT03385980 | Donation of Post Mortem Tumor Tissues(DONUM) | completed | — | 20 | Niguarda HospitalOTHER | 1 | Mar 22, 2023 | clinicaltrials |
| NCT04080414 | Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence | completed | N/A | 7 | University of UtahOTHER | 1 | Mar 22, 2023 | clinicaltrials |
| NCT03801915 | Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers | completed | Phase 2 | 10 | National Cancer Institute (NCI)NIH | 1 | Mar 21, 2023 | clinicaltrials |
| NCT05772923 | Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision(OPAXX) | recruiting | N/A | 168 | The Netherlands Cancer InstituteOTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT05733000 | CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors | recruiting | Phase 2 | 94 | Northwestern UniversityOTHER | 1 | Mar 10, 2023 | clinicaltrials |
| NCT05429866 | Immunological Variables Associated to ICI Toxicity in Cancer Patients | unknown | Phase 2 | 441 | Jules Bordet InstituteOTHER | 1 | Mar 8, 2023 | clinicaltrials |
| NCT02890758 | Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803 | completed | Phase 1 | 14 | Brenda Cooper, MDOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT03871959 | Pembrolizumab In Combination With Debio 1143 In Pancreatic and Colorectal Advanced/Metastatic Adenocarcinoma(CATRIPCA) | completed | Phase 1 | 54 | Centre Leon BerardOTHER | 1 | Feb 17, 2023 | clinicaltrials |
| NCT03871790 | Peptide-based Immunization for Colon- and and Pancreas-carcinoma(PICOP-GLOBAL) | completed | — | 50 | CENTOGENE GmbH RostockINDUSTRY | 1 | Feb 10, 2023 | clinicaltrials |
| NCT05185557 | BRIANSTORM - Early Identification of Patients With Brain Metastases | unknown | — | 50 | Aarhus University HospitalOTHER | 1 | Feb 3, 2023 | clinicaltrials |
| NCT04980443 | Evaluation of a New Blood-based Test to Detect Colorectal Cancer and Its Precursors(CELTiC) | completed | N/A | 809 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 2 | Feb 1, 2023 | clinicaltrials |
| NCT05685680 | Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma | unknown | N/A | 50 | Sohag UniversityOTHER | 1 | Jan 17, 2023 | clinicaltrials |
| NCT03078361 | Latinos CARES (Colorectal Cancer Awareness, Research, Education and Screening) | completed | N/A | 159 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT04833387 | PD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer | active not recruiting | Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT05314309 | Prospective Clinical Validation of a Novel Multitarget FIT in CRC Screening(mtFIT) | unknown | — | 14,712 | The Netherlands Cancer InstituteOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT04044430 | Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer | terminated | Phase 1 | 2 | University of California, San FranciscoOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT03297710 | TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery | completed | Phase 1 | 7 | Mayo ClinicOTHER | 1 | Jan 5, 2023 | clinicaltrials |
| NCT05236972 | PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer | recruiting | Phase 3 | 323 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2022 | clinicaltrials |
| NCT05667259 | Prognostic Significance of Lymph Node Ratio in Rectal Cancer on Overall Survival | completed | — | 229 | South Valley UniversityOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05368688 | Microbiome in Colorectal Cancer Onset and Progression | terminated | — | 63 | ViomeINDUSTRY | 1 | Dec 27, 2022 | clinicaltrials |
| NCT05291988 | A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial | terminated | N/A | 8 | Fred Hutchinson Cancer CenterOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT05645094 | Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer | unknown | — | 38 | Fudan UniversityOTHER | 0 | Dec 13, 2022 | clinicaltrials |
| NCT05635149 | Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal Cancer | unknown | — | 100 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT03517488 | A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors(DUET-2) | completed | Phase 1 | 150 | Xencor, Inc.INDUSTRY | 1 | Dec 1, 2022 | clinicaltrials |
| NCT05477836 | Feasibility and Safety of MiWEndo-assisted Colonoscopy(MiWEndo1) | completed | N/A | 15 | MiWEndo Solutions S.L.INDUSTRY | 1 | Nov 30, 2022 | clinicaltrials |
| NCT05622357 | Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer | completed | Phase 2 | 51 | National Cancer Institute, EgyptOTHER | 1 | Nov 18, 2022 | clinicaltrials |
| NCT04281667 | Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery(MOBILE2) | active not recruiting | Phase 4 | 604 | Helsinki University Central HospitalOTHER | 1 | Nov 17, 2022 | clinicaltrials |
| NCT05359393 | A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis(Miracle-1) | not yet recruiting | Phase 2 | 52 | Fudan UniversityOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT03078348 | Increasing Access to Colorectal Cancer Testing (IACCT) for Blacks(IACCT) | completed | N/A | 331 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Nov 9, 2022 | clinicaltrials |
| NCT05592873 | Oncological Impact of Lateral Nodes in Rectal Cancer(I-ONARC) | completed | — | 317 | Niguarda HospitalOTHER | 0 | Oct 25, 2022 | clinicaltrials |
| NCT03693846 | Nivolumab and Ipilimumab in Mucinous Colorectal and Appendiceal Tumors | terminated | Phase 2 | 11 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Oct 20, 2022 | clinicaltrials |
| NCT02713373 | Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery | completed | Phase 1 / Phase 2 | 45 | Roswell Park Cancer InstituteOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT03781778 | Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors | terminated | Phase 2 | 10 | Fred Hutchinson Cancer CenterOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT04673955 | BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment(BERING-CRC) | recruiting | — | 500 | Pierre Fabre Pharma GmbHINDUSTRY | 2 | Sep 29, 2022 | clinicaltrials |
| NCT03965845 | A Study of Telaglenastat (CB-839) in Combination With Palbociclib in Patients With Solid Tumors | completed | Phase 1 / Phase 2 | 53 | Calithera Biosciences, IncINDUSTRY | 1 | Sep 19, 2022 | clinicaltrials |
| NCT05091528 | A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers | terminated | Phase 1 / Phase 2 | 2 | Silverback TherapeuticsINDUSTRY | 1 | Aug 18, 2022 | clinicaltrials |
| NCT05493930 | A Lymph Node Metastasis Predictor (LN-MASTER) in Rectal Cancer | completed | — | 6,578 | Peking Union Medical CollegeOTHER | 0 | Aug 9, 2022 | clinicaltrials |
| NCT04208724 | Support Program for Adoption of Cancer Screening Interventions at a Rural Community-Based Organization | completed | N/A | 35 | Fred Hutchinson Cancer CenterOTHER | 1 | Jul 26, 2022 | clinicaltrials |
| NCT01896778 | Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer | completed | N/A | 9 | Roswell Park Cancer InstituteOTHER | 1 | Jul 25, 2022 | clinicaltrials |
| NCT05021172 | Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults | completed | N/A | 75 | University of California, San FranciscoOTHER | 1 | Jul 11, 2022 | clinicaltrials |
| NCT05422547 | Role of Immunoscore® in Stage II-III Colorectal Cancer | unknown | — | 100 | D'Or Institute for Research and EducationOTHER | 1 | Jun 16, 2022 | clinicaltrials |
| NCT05411783 | Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial(LOTHVEIN) | unknown | N/A | 84 | San Carlo di Nancy HospitalOTHER | 1 | Jun 9, 2022 | clinicaltrials |
| NCT05406206 | Hepatic Arterial Infusion Chemotherapy With Fruquintinib for Colorectal Cancer Liver Metastases As Third-line Therapy | unknown | Phase 2 | 27 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 6, 2022 | clinicaltrials |
| NCT03332498 | Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal Cancers | completed | Phase 1 / Phase 2 | 40 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Jun 3, 2022 | clinicaltrials |
| NCT03958500 | The Problem of Colorectal Anastomosis Safety(ANSCRS) | completed | N/A | 60 | Vilnius UniversityOTHER | 1 | Jun 3, 2022 | clinicaltrials |
| NCT02218801 | A Prospective Colorectal Liver Metastasis Database With an Integrated Quality Assurance Program(CLIMB) | completed | — | 219 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 12 | May 31, 2022 | clinicaltrials |
Data updated 23 days agoSource updated May 6, 2023source: clinicaltrials