Clinical trial · Interventional
PR in Endoscopic LAR for Rectal Cancer
Pelvic Floor Reconstruction (PR) in Endoscopic Low Anterior Resection for Rectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The anastomotic leakage remains the major early complication after laparoscopic anterior resection(LAR) for medium \& low rectal cancer. Pelvic floor reconstruction (PR) is a key step in various standard resections for open radical rectal cancer surgery, which was considered to be helpful for decreasing the rate of leakage. However, PR in endoscopic LAR surgery is not routine practice and remains controversial. The purpose of this study is to evaluate the efficacy of PR during LAR for mid/low rectal carcinoma, especially in preventing anastomotic leakage.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Carcinoma | Rectal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pelvic floor Reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PR
- interventionNames
- Procedure: Pelvic floor Reconstruction
- type
- ACTIVE_COMPARATOR
- label
- Non-PR
- interventionNames
- Procedure: Pelvic floor Reconstruction
Primary outcomes (3)
- measure
- The rate of anastomotic leakage after laparoscopic anterior resection for rectal cancer
- timeFrame
- 30 days after surgery
- measure
- Re-operation rate after anastomotic leakage
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients with histologically proven rectal adenocarcinoma 2. tumor located in the middle and lower rectum and anastomosis under the peritoneal reflection 3. Tumor assessed as a depth of invasion that was confined to pT1-pT3, bN0-1M0 by ultrasound colonoscopy and/or pelvic MRI 4. Negative circumferential resection margin confirmed by MRI 5. Performance status (ECOG) 0\~1 6. Written informed consent for participation in the trial Exclusion Criteria: 1. History of accepting lower abdominal surgery. 2. More than one colorectal tumor 3. Patients with unresectable distant metastasis or multiple metastases 4. Received neoadjuvant radiotherapy before surgery 5. Signs of acute intestinal obstruction, bleeding or perforation needing emergency surgery 6. Patients and/or family members cannot understand and accept this study 7. Non-rectal adenocarcinoma was confirmed by postoperative pathological examination
References
Publications (0)
Data not yet available