Melphalan

Curated

← predicts response to

KRAS G12SSNV

3 source records aggregated

resistance

Curated

← predicts response to

KRAS G12CSNV

3 source records aggregated

resistance

Curated

← predicts response to

KRAS G12DSNV

3 source records aggregated

resistance

Curated

← predicts response to

KRAS G12ASNV

3 source records aggregated

resistance

Curated

Malignant Pancreatic Neoplasm

← predicts response to

FANCC Loss-of-function

sensitivity

Curated

Melphalan investigated for …INVESTIGATED_FOR70 of 70show fewer
→ investigated for	Multiple Myelomahematologic_malignancy	supports	B	Multiple Myeloma	1	Curated	civic	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	4	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	4	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Neuroblastomasubtype	unknown	4	Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	4	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	4	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	4	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	4	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	4	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	3	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Uveal Melanomasubtype	unknown	3	Uveal Melanoma	1	Curated	chembl	graph →
→ investigated for	Plasma Cell Neoplasmhematologic_malignancy	unknown	3	Plasma Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	AL Amyloidosishematologic_malignancy	unknown	3	AL Amyloidosis	1	Curated	chembl	graph →
→ investigated for	Retinoblastomasubtype	unknown	3	Retinoblastoma	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	3	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ganglioneuroblastomasubtype	unknown	3	Ganglioneuroblastoma	1	Curated	chembl	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	unknown	3	Mantle Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Smoldering Multiple Myelomahematologic_malignancy	unknown	3	Smoldering Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	3	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	3	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	3	Leukemia	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	3	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Ewing Sarcomasubtype	unknown	3	Ewing Sarcoma	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	3	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	3	Melanoma	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy 12 source records aggregated	supports	D	Multiple Myeloma	12	Curated	civic	graph →
→ investigated for	Malignant Pancreatic Neoplasmcancer	supports	D	Malignant Pancreatic Neoplasm	1	Curated	civic	graph →
→ investigated for	Retinal Neoplasmcancer_family	unknown	2	Retinal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy	unknown	2	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy	unknown	2	Myelodysplastic/Myeloproliferative Neoplasm	1	Curated	chembl	graph →
→ investigated for	Adult T-Cell Leukemia/Lymphomahematologic_malignancy	unknown	2	Adult T-Cell Leukemia/Lymphoma	1	Curated	chembl	graph →
→ investigated for	T-Cell Large Granular Lymphocyte Leukemiahematologic_malignancy	unknown	2	T-Cell Large Granular Lymphocyte Leukemia	1	Curated	chembl	graph →
→ investigated for	T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	2	T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	2	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	2	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Carcinomasubtype	unknown	2	Neuroendocrine Carcinoma	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	2	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Myeloproliferative Neoplasmhematologic_malignancy	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
→ investigated for	Chronic Myelomonocytic Leukemiahematologic_malignancy	unknown	2	Chronic Myelomonocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Mycosis Fungoideshematologic_malignancy	unknown	2	Mycosis Fungoides	1	Curated	chembl	graph →
→ investigated for	Sezary Syndromehematologic_malignancy	unknown	2	Sezary Syndrome	1	Curated	chembl	graph →
→ investigated for	Waldenstrom Macroglobulinemiahematologic_malignancy	unknown	2	Waldenstrom Macroglobulinemia	1	Curated	chembl	graph →
→ investigated for	Plasmacytomahematologic_malignancy	unknown	2	Plasmacytoma	1	Curated	chembl	graph →
→ investigated for	Anaplastic Large Cell Lymphomahematologic_malignancy	unknown	2	Anaplastic Large Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Polycythemia Verahematologic_malignancy	unknown	2	Polycythemia Vera	1	Curated	chembl	graph →
→ investigated for	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy	unknown	2	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type	1	Curated	chembl	graph →
→ investigated for	Acute Erythroid Leukemiahematologic_malignancy	unknown	2	Acute Erythroid Leukemia	1	Curated	chembl	graph →
→ investigated for	Juvenile Myelomonocytic Leukemiahematologic_malignancy	unknown	2	Juvenile Myelomonocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Breast Inflammatory Carcinomasubtype	unknown	2	Breast Inflammatory Carcinoma	1	Curated	chembl	graph →
→ investigated for	Plasma Cell Leukemiahematologic_malignancy	unknown	2	Plasma Cell Leukemia	1	Curated	chembl	graph →
→ investigated for	Testicular Neoplasmsubtype	unknown	2	Testicular Neoplasm	1	Curated	chembl	graph →
→ investigated for	Medulloblastomasubtype	unknown	2	Medulloblastoma	1	Curated	chembl	graph →
→ investigated for	Hematopoietic and Lymphoid Cell Neoplasmcancer_family	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	Primary Myelofibrosishematologic_malignancy	unknown	2	Primary Myelofibrosis	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	2	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	2	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Burkitt Lymphomahematologic_malignancy	unknown	2	Burkitt Lymphoma	1	Curated	chembl	graph →
→ investigated for	Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy	unknown	2	Peripheral T-Cell Lymphoma, Not Otherwise Specified	1	Curated	chembl	graph →
→ investigated for	Chronic Lymphocytic Leukemiahematologic_malignancy	unknown	2	Chronic Lymphocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Paragangliomasubtype	unknown	1	Paraganglioma	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	1	Glioma	1	Curated	chembl	graph →
→ investigated for	Lymphoid Leukemiahematologic_malignancy	unknown	1	Lymphoid Leukemia	1	Curated	chembl	graph →
→ investigated for	Chordomacancer_family	unknown	1	Chordoma	1	Curated	chembl	graph →
→ investigated for	Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	1	Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	1	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	1	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Central Nervous System Neoplasmcancer_family	unknown	1	Central Nervous System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Oligodendrogliomasubtype	unknown	1	Oligodendroglioma	1	Curated	chembl	graph →
→ investigated for	Neuroepithelial Neoplasmcancer_family	unknown	0.5	Neuroepithelial Neoplasm	1	Curated	chembl	graph →

Melphalan investigated for …INVESTIGATED_FOR70 of 70show fewer

→ investigated for

Multiple Myelomahematologic_malignancy

supports

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Neuroblastomasubtype

unknown

Neuroblastoma

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

→ investigated for

Uveal Melanomasubtype

unknown

Uveal Melanoma

Curated

→ investigated for

Plasma Cell Neoplasmhematologic_malignancy

unknown

Plasma Cell Neoplasm

Curated

→ investigated for

AL Amyloidosishematologic_malignancy

unknown

AL Amyloidosis

Curated

→ investigated for

Retinoblastomasubtype

unknown

Retinoblastoma

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Ganglioneuroblastomasubtype

unknown

Ganglioneuroblastoma

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

unknown

Mantle Cell Lymphoma

Curated

Smoldering Multiple Myeloma

→ investigated for

Smoldering Multiple Myelomahematologic_malignancy

unknown

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

→ investigated for

Ewing Sarcomasubtype

unknown

Ewing Sarcoma

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

12 source records aggregated

supports

Curated

Malignant Pancreatic Neoplasm

→ investigated for

Malignant Pancreatic Neoplasmcancer

supports

Curated

→ investigated for

Retinal Neoplasmcancer_family

unknown

Retinal Neoplasm

Curated

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue

→ investigated for

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy

unknown

Curated

Myelodysplastic/Myeloproliferative Neoplasm

→ investigated for

Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy

unknown

Curated

Adult T-Cell Leukemia/Lymphoma

→ investigated for

Adult T-Cell Leukemia/Lymphomahematologic_malignancy

unknown

Curated

T-Cell Large Granular Lymphocyte Leukemia

→ investigated for

T-Cell Large Granular Lymphocyte Leukemiahematologic_malignancy

unknown

Curated

T-Cell Non-Hodgkin Lymphoma

→ investigated for

T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Neuroendocrine Carcinomasubtype

unknown

Neuroendocrine Carcinoma

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

Myeloproliferative Neoplasm

→ investigated for

Myeloproliferative Neoplasmhematologic_malignancy

unknown

Curated

Chronic Myelomonocytic Leukemia

→ investigated for

Chronic Myelomonocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Mycosis Fungoideshematologic_malignancy

unknown

Mycosis Fungoides

Curated

→ investigated for

Sezary Syndromehematologic_malignancy

unknown

Sezary Syndrome

Curated

Waldenstrom Macroglobulinemia

→ investigated for

Waldenstrom Macroglobulinemiahematologic_malignancy

unknown

Curated

→ investigated for

Plasmacytomahematologic_malignancy

unknown

Plasmacytoma

Curated

Anaplastic Large Cell Lymphoma

→ investigated for

Anaplastic Large Cell Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Polycythemia Verahematologic_malignancy

unknown

Polycythemia Vera

Curated

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type

→ investigated for

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy

unknown

Curated

→ investigated for

Acute Erythroid Leukemiahematologic_malignancy

unknown

Acute Erythroid Leukemia

Curated

Juvenile Myelomonocytic Leukemia

→ investigated for

Juvenile Myelomonocytic Leukemiahematologic_malignancy

unknown

Curated

Breast Inflammatory Carcinoma

→ investigated for

Breast Inflammatory Carcinomasubtype

unknown

Curated

→ investigated for

Plasma Cell Leukemiahematologic_malignancy

unknown

Plasma Cell Leukemia

Curated

→ investigated for

Testicular Neoplasmsubtype

unknown

Testicular Neoplasm

Curated

→ investigated for

Medulloblastomasubtype

unknown

Medulloblastoma

Curated

Hematopoietic and Lymphoid Cell Neoplasm

→ investigated for

Hematopoietic and Lymphoid Cell Neoplasmcancer_family

unknown

Curated

→ investigated for

Primary Myelofibrosishematologic_malignancy

unknown

Primary Myelofibrosis

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

→ investigated for

Burkitt Lymphomahematologic_malignancy

unknown

Burkitt Lymphoma

Curated

Peripheral T-Cell Lymphoma, Not Otherwise Specified

→ investigated for

Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy

unknown

Curated

Chronic Lymphocytic Leukemia

→ investigated for

Chronic Lymphocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Paragangliomasubtype

unknown

Paraganglioma

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Lymphoid Leukemiahematologic_malignancy

unknown

Lymphoid Leukemia

Curated

→ investigated for

Chordomacancer_family

unknown

Chordoma

Curated

Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated for

Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

Central Nervous System Neoplasm

→ investigated for

Central Nervous System Neoplasmcancer_family

unknown

Curated

→ investigated for

Oligodendrogliomasubtype

unknown

Oligodendroglioma

Curated

→ investigated for

Neuroepithelial Neoplasmcancer_family

unknown

0.5

Neuroepithelial Neoplasm

Curated

Melphalan investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 272show all (up to 200)
→ investigated in trials for	Multiple Myelomahematologic_malignancy 172 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Multiple Myeloma	172	Observed	clinicaltrials	graph →
→ investigated in trials for	Lymphomacancer_family 109 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lymphoma	109	Observed	clinicaltrials	graph →
→ investigated in trials for	Myelodysplastic Syndromehematologic_malignancy 86 trials (26 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myelodysplastic Syndrome	86	Observed	clinicaltrials	graph →
→ investigated in trials for	Leukemiacancer_family 67 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Leukemia	67	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Myeloid Leukemiahematologic_malignancy 53 trials (24 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Myeloid Leukemia	53	Observed	clinicaltrials	graph →
→ investigated in trials for	Neuroblastomasubtype 39 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Neuroblastoma	39	Observed	clinicaltrials	graph →
→ investigated in trials for	Non-Hodgkin Lymphomahematologic_malignancy 37 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Non-Hodgkin Lymphoma	37	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Lymphoblastic Leukemiahematologic_malignancy 36 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Lymphoblastic Leukemia	36	Observed	clinicaltrials	graph →
→ investigated in trials for	Hodgkin Lymphomahematologic_malignancy 31 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hodgkin Lymphoma	31	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Lymphocytic Leukemiahematologic_malignancy 22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Lymphocytic Leukemia	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Hematopoietic and Lymphoid Cell Neoplasmcancer_family 21 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hematopoietic and Lymphoid Cell Neoplasm	21	Observed	clinicaltrials	graph →
→ investigated in trials for	Myeloproliferative Neoplasmhematologic_malignancy 20 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myeloproliferative Neoplasm	20	Observed	clinicaltrials	graph →
→ investigated in trials for	Mantle Cell Lymphomahematologic_malignancy 17 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Mantle Cell Lymphoma	17	Observed	clinicaltrials	graph →
→ investigated in trials for	Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy 16 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myelodysplastic/Myeloproliferative Neoplasm	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 15 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	15	Observed	clinicaltrials	graph →

Melphalan investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 272show all (up to 200)

→ investigated in trials for

Multiple Myelomahematologic_malignancy

172 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

172

Observed

→ investigated in trials for

Lymphomacancer_family

109 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lymphoma

109

Observed

→ investigated in trials for

Myelodysplastic Syndromehematologic_malignancy

86 trials (26 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Myelodysplastic Syndrome

Observed

→ investigated in trials for

Leukemiacancer_family

67 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Leukemia

Observed

→ investigated in trials for

Acute Myeloid Leukemiahematologic_malignancy

53 trials (24 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Acute Myeloid Leukemia

Observed

→ investigated in trials for

Neuroblastomasubtype

39 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Neuroblastoma

Observed

→ investigated in trials for

Non-Hodgkin Lymphomahematologic_malignancy

37 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Non-Hodgkin Lymphoma

Observed

Acute Lymphoblastic Leukemia

→ investigated in trials for

Acute Lymphoblastic Leukemiahematologic_malignancy

36 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Hodgkin Lymphomahematologic_malignancy

31 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Hodgkin Lymphoma

Observed

Chronic Lymphocytic Leukemia

→ investigated in trials for

Chronic Lymphocytic Leukemiahematologic_malignancy

22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Hematopoietic and Lymphoid Cell Neoplasm

→ investigated in trials for

Hematopoietic and Lymphoid Cell Neoplasmcancer_family

21 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Myeloproliferative Neoplasm

→ investigated in trials for

Myeloproliferative Neoplasmhematologic_malignancy

20 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Mantle Cell Lymphomahematologic_malignancy

17 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Mantle Cell Lymphoma

Observed

Myelodysplastic/Myeloproliferative Neoplasm

→ investigated in trials for

Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy

16 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated in trials for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

15 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Melphalan studied in …STUDIED_INderived10 of 578show all (up to 200)
→ studied in	NCT06377540Phase 2 · recruiting MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma · 578 trials list this drug (82 active)	—	—	Classic Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07605416Phase 2 · recruiting Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial · 578 trials list this drug (82 active)	—	—	Plasma Cell Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03494569Phase 1 · suspended Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome · 578 trials list this drug (82 active)	—	—	Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome,Secondary Acute Myeloid Leukemia+1	1	Observed	clinicaltrials	graph →
→ studied in	NCT05564390Phase 2 · recruiting MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) · 578 trials list this drug (82 active)	—	—	Myelodysplastic Syndrome,Acute Myeloid Leukemia,Acute Myeloid Leukemia Arising from Previous Myelodysplastic/Myeloproliferative Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT06172296Phase 3 · recruiting Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma · 578 trials list this drug (82 active)	—	—	Neuroblastoma,Ganglioneuroblastoma, Nodular	1	Observed	clinicaltrials	graph →
→ studied in	NCT01857934Phase 2 · completed Therapy for Children With Advanced Stage Neuroblastoma · 578 trials list this drug (82 active)	—	—	Neuroblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03004287Phase 2 · active not recruiting 2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy · 578 trials list this drug (82 active)	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03849651Phase 2 · active not recruiting TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies · 578 trials list this drug (82 active)	—	—	Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Juvenile Myelomonocytic Leukemia+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT01279694Phase 1/Phase 2 · completed Trial of Carfilzomib Plus Melphalan and Prednisone in Elderly Untreated Patients With Multiple Myeloma (CARMYSAP) · 578 trials list this drug (82 active)	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05436418Phase 1/Phase 2 · recruiting The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation · 578 trials list this drug (82 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →

Melphalan studied in …STUDIED_INderived10 of 578show all (up to 200)

→ studied in

NCT06377540Phase 2 · recruiting

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma · 578 trials list this drug (82 active)

—

Classic Hodgkin Lymphoma

Observed

→ studied in

NCT07605416Phase 2 · recruiting

Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial · 578 trials list this drug (82 active)

—

Plasma Cell Leukemia

Observed

Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome,Secondary Acute Myeloid Leukemia+1

→ studied in

NCT03494569Phase 1 · suspended

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome · 578 trials list this drug (82 active)

—

Observed

Myelodysplastic Syndrome,Acute Myeloid Leukemia,Acute Myeloid Leukemia Arising from Previous Myelodysplastic/Myeloproliferative Neoplasm+2

→ studied in

NCT05564390Phase 2 · recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) · 578 trials list this drug (82 active)

—

Observed

Neuroblastoma,Ganglioneuroblastoma, Nodular

→ studied in

NCT06172296Phase 3 · recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma · 578 trials list this drug (82 active)

—

Observed

→ studied in

NCT01857934Phase 2 · completed

Therapy for Children With Advanced Stage Neuroblastoma · 578 trials list this drug (82 active)

—

Neuroblastoma

Observed

→ studied in

NCT03004287Phase 2 · active not recruiting

2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy · 578 trials list this drug (82 active)

—

Observed

Acute Lymphoblastic Leukemia,Hodgkin Lymphoma,Juvenile Myelomonocytic Leukemia+2

→ studied in

NCT03849651Phase 2 · active not recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies · 578 trials list this drug (82 active)

—

Observed

→ studied in

NCT01279694Phase 1/Phase 2 · completed

Trial of Carfilzomib Plus Melphalan and Prednisone in Elderly Untreated Patients With Multiple Myeloma (CARMYSAP) · 578 trials list this drug (82 active)

—

Observed

→ studied in

NCT05436418Phase 1/Phase 2 · recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation · 578 trials list this drug (82 active)

—

not mapped

Observed