Small Lymphocytic Lymphoma — Genomics · CancerIndex

Small Lymphocytic Lymphoma — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

6 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Chronic Lymphocytic Leukemia (Broad, Cell 2013) lcll_broad_2013Broad

160 cases with simple somatic mutation data · 160 cases total · 2026-01-07 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SF3B1	Ssm	23	160	14.4%	cbioportal
2	TP53	Ssm	19	160	11.9%	cbioportal
3	NOTCH1	Ssm	15	160	9.4%	cbioportal
4	MYD88	Ssm	12	160	7.5%	cbioportal
5	ATM	Ssm	9	160	5.6%	cbioportal
6	CHD2	Ssm	6	160	3.8%	cbioportal
7	MUC16	Ssm	6	160	3.8%	cbioportal
8	FAT3

Data updated 22 days agoSource updated 2026-01-07

Chronic Lymphocytic Leukemia (Broad, Nature 2015) cll_broad_2015Broad

537 cases with simple somatic mutation data · 537 cases total · 2026-01-06 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SF3B1

Chronic Lymphocytic Leukemia (Broad, Nature Genetics 2022) cll_broad_2022Broad

1,075 cases with simple somatic mutation data · 1,154 cases total · 2026-02-19 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SF3B1

Chronic lymphocytic leukemia (ICGC, Nature Genetics 2011) cllsll_icgc_2011ICGC

105 cases with simple somatic mutation data · 105 cases total · 2026-01-06 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SF3B1

Chronic Lymphocytic Leukemia (IUOPA, Nature 2015) cll_iuopa_2015IUOPA

506 cases with simple somatic mutation data · 506 cases total · 2026-01-06 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	NOTCH1

Chronic Lymphocytic Leukemia (MSK, 2026) cllsll_msk_2026MSK

21 cases with simple somatic mutation data · 21 cases total · 2026-03-25 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SF3B1	Ssm	14

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.