Gene
ITGA2B
integrin subunit alpha 2b
Explore in graph →CI-GENE-00006404HGNC:6138 ENSG00000005961 NCBI 3674 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22561520
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma (National University of Singapore, Nat Genet 2012) chol_nus_2012 | Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 80 | cbioportal |
| Normal Keratinocytes (UCSF, BioRxiv 2024) normal_skin_keratinocytes_2024 | unmapped | Ssm | 8 | 136 | 5.9% | 102 | cbioportal |
| Chronic lymphocytic leukemia (ICGC, Nature Genetics 2011) cllsll_icgc_2011 | Small Lymphocytic Lymphoma | Ssm | 2 | 105 | 1.9% | 44 | cbioportal |
| Prostate Adenocarcinoma (CPC-GENE, Nature 2017) prad_cpcg_2017 | Prostate Adenocarcinoma | Ssm | 3 | 477 | 0.6% | 144 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.