Cancer
Malignant Rectal Neoplasm
CI-CAN-00008012Explore in graph →
Top-level388 active trials1 approved drugs5 evidence items
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Cancer
CI-CAN-00008012Explore in graph →
Clinical trials
1,551 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (153)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05201872 | Bacteriological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. | unknown | — | 216 | Yanhong DengOTHER | 1 | Feb 7, 2022 | clinicaltrials |
| NCT05201885 | Oncological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. | unknown | — | 192 | Yanhong DengOTHER | 1 | Feb 3, 2022 | clinicaltrials |
| NCT04790227 | MRI for Selection of Complete Responders After Chemoradiation for Locally Advanced Rectal Cancer | unknown | — | 50 | Assiut UniversityOTHER | 1 | Feb 1, 2022 | clinicaltrials |
| NCT02279771 | Transanal Reinforcement of Low Rectal Anastomosis in Rectal Cancer Surgery(LessStoReS) | unknown | N/A | 140 | Donato F AltomareNETWORK | 1 | Jan 11, 2022 | clinicaltrials |
| NCT03581344 | BReak Interval Delayed Surgery for Gastrointestinal Extraperitoneal Rectal Cancer(BRIDGE) | unknown | N/A | 148 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Jan 11, 2022 | clinicaltrials |
| NCT03597126 | Short Term Outcomes of Robotic-assisted Intersphincteric Resection for Low Rectal Cancer(R-ISR) | unknown | N/A | 100 | Southwest Hospital, ChinaOTHER | 1 | Dec 9, 2021 | clinicaltrials |
| NCT04078828 | PR in Endoscopic LAR for Rectal Cancer | unknown | N/A | 10 | Southwest Hospital, ChinaOTHER | 1 | Nov 30, 2021 | clinicaltrials |
| NCT04065984 | Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)(BiCyCLE-NMES) | unknown | N/A | 46 | London North West Healthcare NHS TrustOTHER | 1 | Oct 29, 2021 | clinicaltrials |
| NCT04948762 | A Contemporary Review of Surgical Approaches in Pelvic Exenterative Surgery | unknown | — | 1,000 | St Vincent's University Hospital, IrelandOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT05079438 | Dendrobium Huoshanense Suppository in Rectal Cancer | unknown | Phase 3 | 168 | Zhejiang Cancer HospitalOTHER | 1 | Oct 15, 2021 | clinicaltrials |
| NCT05079503 | Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer | unknown | N/A | 40 | Korean Cancer Study GroupOTHER | 0 | Oct 15, 2021 | clinicaltrials |
| NCT05076305 | PelvEx 4: Advanced Pelvic Malignancy and the Role of the Multi-disciplinary Team Meeting | unknown | — | 12 | St Vincent's University Hospital, IrelandOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT01899547 | Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum(LASRE) | unknown | N/A | 1,070 | Fujian Medical UniversityOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT05028192 | Mitochondria Preservation by Exercise Training: a Targeted Therapy for Cancer and Chemotherapy-induced Cachexia(MEx) | unknown | — | 144 | University of Turin, ItalyOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT02948348 | Study to Nivolumab Following Preoperative Chemoradiotherapy | unknown | Phase 1 / Phase 2 | 90 | Takayuki YoshinoOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT02406118 | Phase II Clinical Trial for the Evaluation of the Efficacy of Transanal TME | unknown | N/A | 49 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 10, 2021 | clinicaltrials |
| NCT02421432 | Evaluation of the Safety and the Efficacy of Transanal TME in Difficult Cases | unknown | N/A | 12 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 10, 2021 | clinicaltrials |
| NCT04287400 | Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer | unknown | — | 210 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 5, 2021 | clinicaltrials |
| NCT05020613 | Early and Late Removal of the Urinary Catheter After Rectum Resection | unknown | N/A | 120 | Marmara UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT04267575 | Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites | unknown | N/A | 20 | Jerome Canady, M.D.OTHER | 1 | Aug 9, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04970498 | Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer | unknown | — | 120 | Peking University Third HospitalOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT02533271 | Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer(STELLAR) | unknown | Phase 3 | 600 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT02546596 | The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer | unknown | N/A | 76 | Yonsei Hyperthermia Study GroupOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT04293419 | Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer(DUREC) | unknown | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT04664504 | A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk | unknown | Phase 2 | 150 | Jing Jin, M.D.UNKNOWN | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04917263 | IMMUNOlogical Microenvironment in REctal Adenocarcinoma Treatment.(IMMUNOREACT2) | unknown | — | 544 | University of PadovaOTHER | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04672603 | Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer | unknown | N/A | 214 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT04850027 | MRI-guided Lateral Lymph Node Dissection in Rectal Cancer | unknown | — | 268 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 26, 2021 | clinicaltrials |
| NCT02167321 | Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision | unknown | Phase 2 | 90 | Yonsei UniversityOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT04848311 | Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253 | unknown | N/A | 66 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT04838496 | Induction Chemotherapy for Locally Advanced Rectal Cancer(MEND-IT) | unknown | Phase 2 | 128 | Catharina Ziekenhuis EindhovenOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT02752698 | Domestic Surgical Robot Clinical Study | unknown | N/A | 200 | The Third Xiangya Hospital of Central South UniversityOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT04814784 | Role of Neoadjuvent Radiotherapy in Locally Advanced Cancer Rectum | unknown | — | 48 | Amany sayed AbassOTHER | 1 | Mar 24, 2021 | clinicaltrials |
| NCT04423965 | A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC | unknown | Phase 2 | 220 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer(CORT) | unknown | Phase 2 | 60 | Zhou FuxiangOTHER | 1 | Mar 17, 2021 | clinicaltrials |
| NCT04747951 | Total Neoadjuvant Therapy in Rectal Cancer Treatment | unknown | Phase 4 | 280 | State Scientific Centre of Coloproctology, Russian FederationOTHER_GOV | 1 | Feb 15, 2021 | clinicaltrials |
| NCT04749381 | The Role of TCM on ERAS of Rectal Cancer Patients(RCT) | unknown | Phase 2 | 264 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 11, 2021 | clinicaltrials |
| NCT04751149 | Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection(RAOREC) | unknown | N/A | 143 | Hospital DonostiaOTHER | 1 | Feb 11, 2021 | clinicaltrials |
| NCT04103697 | Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer(RuCorT-01) | unknown | Phase 3 | 560 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04134897 | Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer(RuCorT-02) | unknown | Phase 3 | 316 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04135313 | Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer(RuCorT-03) | unknown | Phase 3 | 540 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04745091 | MRI Split Scar Sign as a Predictor to Complete Pathologic Response After Neoadjuvant Chemoradiation in Rectal Cancer | unknown | — | 20 | Alexandria UniversityOTHER | 0 | Feb 9, 2021 | clinicaltrials |
| NCT04717947 | Interval Between Neoadjuvant Therapy and Surgery in the Treatment of Locally Advanced Rectal Cancer (CRONOS)(CRONOS) | unknown | — | 911 | Hospital Clinic of BarcelonaOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04738214 | Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients | unknown | — | 39 | Yonsei UniversityOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04735107 | Mucosal Flap Reinforced Colorectal Anastomosis and Trans-Anal Vacuum Drainage: A Feasibility Study(Endodrain) | unknown | N/A | 50 | Comenius UniversityOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04710589 | CTV Exploration of 3D-PT Assisted CT-guided I-125 Seeds Implantation for Recurrent Rectal Cancer | unknown | — | 60 | Peking University Third HospitalOTHER | 1 | Jan 14, 2021 | clinicaltrials |
| NCT04674696 | Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer(SHORT-ICAR) | unknown | Phase 2 | 54 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Dec 19, 2020 | clinicaltrials |
| NCT04663763 | Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 | 40 | Zhejiang Cancer HospitalOTHER | 1 | Dec 11, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Feb 7, 2022source: clinicaltrials