Subtype
Malignant Bone Neoplasm
CI-CAN-00001109Explore in graph →
38 active trials4 approved drugs8 evidence items
- NCIt
- C4016
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Subtype
CI-CAN-00001109Explore in graph →
Clinical trials
152 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (18)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02811523 | In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma | recruiting | Phase 1 | 17 | University Health Network, TorontoOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT03160274 | Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions | recruiting | — | 2,000 | The University of Texas Health Science Center at San AntonioOTHER | 1 | Oct 15, 2025 | clinicaltrials |
| NCT03244020 | LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology | enrolling by invitation | Phase 4 | 2,868 | Massachusetts General HospitalOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT02880319 | Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone | active not recruiting | Phase 2 | 150 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT07145931 | Neoadjuvant Immunochemotherapy and Postoperative Adjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma Invading the Skull Base | not yet recruiting | Phase 2 | 24 | Sun Yat-sen UniversityOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07018960 | "Multicenter Registry for Chest Wall Reconstruction Using Custom Dynamic Prostheses (PRODIPET)"(PRODIPET) | recruiting | N/A | 60 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y CajalOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT07113301 | Incisional Biopsy Versus Core-needle Biopsy in Bone Tumors Analysis(INSPECTOR) | active not recruiting | — | 42 | Istituto Ortopedico RizzoliOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT05947149 | HRQoL in Patients With Solid Tumors Treated With Hadrontherapy(HadroQoL) | recruiting | — | 180 | CNAO National Center of Oncological HadrontherapyOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT06522165 | Pediatric Oncological Orthopaedic Reconstruction | active not recruiting | — | 400 | Costantino ErraniOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT07066982 | Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas(BAH2573-103) | recruiting | Phase 1 / Phase 2 | 60 | Essen BiotechOTHER | 1 | Jul 15, 2025 | clinicaltrials |
| NCT00592293 | Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas | completed | N/A | 70 | Massachusetts General HospitalOTHER | 1 | Jul 3, 2025 | clinicaltrials |
| NCT04181970 | Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK((SELNET)) | recruiting | — | 5,000 | Grupo Espanol de Investigacion en SarcomasOTHER | 8 | Mar 21, 2025 | clinicaltrials |
| NCT06850506 | Exploring the Expression Level of Cadherin 6 Protein (CDH6) in Primary Malignant Bone Tumor Specimens and Its Clinical Application in Prognosis Assessment | active not recruiting | — | 70 | Peking University People's HospitalOTHER | 1 | Feb 27, 2025 | clinicaltrials |
| NCT05131815 | The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors | completed | N/A | 8 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT03154190 | Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer | completed | N/A | 128 | Stanford UniversityOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT04974008 | Osteosarcoma Maintenance Therapy With OST31-164(OST-164-01) | active not recruiting | Phase 2 | 39 | Emerald Clinical Inc.INDUSTRY | 1 | Jan 22, 2025 | clinicaltrials |
| NCT04410042 | Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure | terminated | Phase 3 | 15 | St. Jude Children's Research HospitalOTHER | 1 | Dec 20, 2024 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT04755140 | Endoprosthesis Metal Toxicity Study | completed | — | 20 | Mayo ClinicOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT04963517 | Exercise Intervention for Bone Tumor Patients(proGAIT) | completed | Phase 2 / Phase 3 | 11 | Universität Duisburg-EssenOTHER | 1 | Dec 6, 2024 | clinicaltrials |
| NCT06669013 | Chemo-immunotherapy in Patients Under 18 Years of Age With Bone and Soft Tissue Sarcomas(FollowTheDIN) | recruiting | Phase 3 | 40 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | Nov 1, 2024 | clinicaltrials |
| NCT06637007 | Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma | recruiting | Phase 2 | 30 | Shanxi Province Cancer HospitalOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT03277924 | Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas(ImmunoSarc) | completed | Phase 1 / Phase 2 | 197 | Grupo Espanol de Investigacion en SarcomasOTHER | 3 | Aug 13, 2024 | clinicaltrials |
| NCT01803152 | Dendritic Cell Vaccine for Children and Adults With Sarcoma | completed | Phase 1 | 19 | Macarena De La Fuente, MDOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT04740749 | Longevity, Functional Status and Quality of Life of the Compress® Compliant Pre-Stress System(Compress) | terminated | N/A | 200 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 1, 2024 | clinicaltrials |
| NCT04296617 | Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors | completed | — | 36 | Mayo ClinicOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT05057130 | Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors | unknown | Phase 2 / Phase 3 | 50 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 1, 2024 | clinicaltrials |
| NCT05057143 | 3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors | unknown | N/A | 30 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 1, 2024 | clinicaltrials |
| NCT06302465 | Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells | recruiting | N/A | 60 | Peking University People's HospitalOTHER | 1 | Mar 29, 2024 | clinicaltrials |
| NCT00019630 | Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00020267 | Vaccine Therapy in Treating Patients With Metastatic Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT04310410 | Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis(PRE-FURTHER) | completed | Phase 1 / Phase 2 | 10 | UMC UtrechtOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT04842071 | 18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment | unknown | Phase 3 | 2,500 | Centre de recherche du Centre hospitalier universitaire de SherbrookeOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT05024253 | Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements. | completed | Phase 3 | 48 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT05598229 | Application of Douyin in Perioperative Period of Malignant Tumor Patients | unknown | N/A | 90 | Henan Cancer HospitalOTHER_GOV | 0 | Feb 7, 2024 | clinicaltrials |
| NCT02384473 | Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma | completed | Early Phase 1 | 25 | University of Southern CaliforniaOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06202599 | Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' Resistance | completed | — | 124 | Peking University People's HospitalOTHER | 1 | Jan 17, 2024 | clinicaltrials |
| NCT01336803 | Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI(Osteosarcoma) | completed | Phase 2 | 32 | Heike E Daldrup-LinkOTHER | 1 | Dec 27, 2023 | clinicaltrials |
| NCT03525392 | Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. | terminated | Phase 1 | 14 | IpsenINDUSTRY | 5 | Dec 12, 2023 | clinicaltrials |
| NCT06153576 | The Value of Systematic Biopsies During Vertebroplasty for the Treatment of Osteoporotic Vertebral Fractures | completed | — | 1,120 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Dec 11, 2023 | clinicaltrials |
| NCT01811394 | Ion Irradiation of Sacrococcygeal Chordoma(ISAC) | unknown | Phase 2 | 100 | Heidelberg UniversityOTHER | 1 | Dec 6, 2023 | clinicaltrials |
| NCT06120426 | En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor. | recruiting | — | 182 | Shanghai Changzheng HospitalOTHER | 1 | Nov 13, 2023 | clinicaltrials |
| NCT04788147 | Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X)(BIOGUIDE-X) | completed | N/A | 30 | RefleXion MedicalINDUSTRY | 1 | Oct 31, 2023 | clinicaltrials |
| NCT06074692 | PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA)(PRIMA) | recruiting | Phase 2 | 86 | Ruijin HospitalOTHER | 1 | Oct 31, 2023 | clinicaltrials |
| NCT02500797 | Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery | completed | Phase 2 | 164 | National Cancer Institute (NCI)NIH | 1 | Oct 17, 2023 | clinicaltrials |
| NCT06070259 | Insights Into Participating in Studies for Bone Cancer | not yet recruiting | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Oct 6, 2023 | clinicaltrials |
| NCT00667342 | A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma | completed | Phase 2 | 43 | St. Jude Children's Research HospitalOTHER | 1 | Aug 7, 2023 | clinicaltrials |
| NCT05707767 | A Prospective Study of Surgical Treatment Strategies for Chordoma | unknown | N/A | 100 | Xuanwu Hospital, BeijingOTHER | 1 | Jul 19, 2023 | clinicaltrials |
| NCT04877587 | Gemcitabine With Ascorbate Including Adolescents | withdrawn | Early Phase 1 | 0 | David DickensOTHER | 1 | Feb 22, 2023 | clinicaltrials |
Data updated 22 days agoSource updated Nov 26, 2025source: clinicaltrials