Clinical trial · Interventional
Exercise Intervention for Bone Tumor Patients
3D Gait Analysis to Determine Functional Limitations and Evaluate a Training Intervention in Young People With Tumor Endoprosthesis of the Lower Extremity
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The proGait-study is a two-arm exercise intervention study for AYA-patients with lower extremity tumor endoprosthesis in the follow-up care. This clinical trial will investigate the effects of an 8-week personalized multi-modal exercise intervention of lower extremity muscles on gait quality in adolescents and young adults with cancer diagnosis beginning at least 12 months after endoprosthesis implantation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Sarcoma | Bone Sarcoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise therapy | Behavioral | — | UNRESOLVED |
| Information | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Exercise therapy
- description
- 8 weeks personalized, multi-modal exercise with focus on lower extremity * Initial consultation with recommendations for general physical activity * Brochure with exercise recommendations * 2x per week multi-modal group-based and supervised exercise (endurance, strength, mobility, coordination) * week 1 and 2 supervised, week 3 and 4 partially supervised, week 5 and 6 only one supervised session, week 7 and 8 last two sessions supervised
- interventionNames
- Behavioral: Exercise therapy
- type
- ACTIVE_COMPARATOR
- label
- Information group
- description
- * Initial consultation with recommendations for general physical activity * Brochure with exercise recommendations.
- interventionNames
- Other: Information
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Adolescents and young adults between 15 and 45 years of age * Completion of acute cancer treatment and receiving follow-up care in Essen (University Hospital Essen) * At least 12 months post endoprosthesis implantation * Signed informed consent (Parents and Patient) Exclusion Criteria: * \<15 years of age, \>45 years of age * time post implantation \<12 months * Medical condition that limits participation in one of the study arms * Inability to follow the training-protocol
References
Publications (1)
- RESULTBasteck S, Guder WK, Dirksen U, Krombholz A, Streitburger A, Reinhardt D, Gotte M. Effects of an Exercise Intervention on Gait Function in Young Survivors of Osteosarcoma with Megaendoprosthesis of the Lower Extremity-Results from the Pilot Randomized Controlled Trial proGAIT. Curr Oncol. 2022 Oct 14;29(10):7754-7767. doi: 10.3390/curroncol29100613. PMID 36290890