Clinical trial · Interventional
3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors
The Use of Individual 3D-implants in the Reconstruction of the Chest Wall in Patients With the Tumor Lesions of the Chest Wall for the Treatment, Restoration, and Improved Quality of Life Compared to Reconstruction With Titanium Plates
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A patient with a tumor lesion of the chest wall undergoes CT scan with a step width of less than 1 mm, then engineers design an individual model to replace the defect. Using a 3D printer, a model is made based on titanium alloy powder. Preoperative preparation takes an average of 14-21 days. The next stage is surgical treatment in the amount of resection of the chest wall with plastic defect with an individual titanium implant. In some cases, the titanium framework is separated from the pleural cavity by a polytetrafluoroethylene plate in order to seal and prevent the development of pulmonary hernias. The advantages of titanium individual prostheses include accurate matching of the implant to the size and characteristics of the defect, individual modeling allows you to repeat the anatomical features of the patient. This method helps to recreate the original shape of the chest, and most importantly, symmetrical, relatively healthy half. With the help of titanium, individualized prostheses are made based on 3D modeling, which will reduce the incidence of complications, accelerate rehabilitation and improve the quality of life of patients with tumor lesions of the chest wall. The postoperative period takes 15-30 days.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chest Wall Sarcoma | Chest Wall Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Chest Wall Tumor | Chest Wall Neoplasm | ALIAS | 0.90 |
| Implant Site Reaction | — | UNRESOLVED | — |
| Sarcoma of Bone | Bone Sarcoma | ALIAS | 0.90 |
| Surgery | — | UNRESOLVED | — |
| Tumor of Bone | Bone Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Implants | Device | — | UNRESOLVED |
| Plates | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Replacement of a defect in the chest wall with an individual implant
- description
- A patient with a tumor lesion of the chest wall undergoes СT scan with a step width of less than 1 mm, then engineers design an individual model to replace the defect. Using a 3D printer, a model is made based on the patient's anthropometric data.
- interventionNames
- Device: Implants
- type
- ACTIVE_COMPARATOR
- label
- Replacement of a defect in the chest wall with titanium plates
- description
- The use of standard titanium plates to replace the chest defect. These plates must be modeled and modified using special equipment intraoperatively, based on the characteristics of the defect after resection.
- interventionNames
- Device: Plates
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Malignant neoplasm of ribs, sternum and clavicle * Malignant neoplasm of the connective and soft tissues of the chest * Neoplasm of uncertain or unknown nature of ribs, sternum and collarbone * Benign neoplasm of ribs, sternum and collarbone * Tumor lesions of the chest wall of any localization, malignant and benign, as well as of an uncertain or unknown nature * For malignant tumors: Grade 1-3 * Lack of distant metastases * Signed informed consent Exclusion Criteria: * Children, women during pregnancy, childbirth, women during breastfeeding. * Military personnel, with the exception of contract military personnel. * Persons with mental disorders. * Persons detained, taken into custody, serving a sentence in the form of restriction of freedom, arrest, imprisonment or administrative arrest. * Patients with distant metastases (except for a solitary focus in the chest wall without other manifestations of the disease) * Inoperable tumor * The presence of another malignant tumor at the time of examination * ECOG 4 * Having an active or chronic fungal / bacterial / viral infection * Uncontrolled chronic diseases of the liver, kidneys in the acute stage * Presence of metastases
References
Publications (0)
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