Clinical trial · Observational
Endoprosthesis Metal Toxicity Study
Evaluation and Clinical Impact of Serum and Blood Metal Ion Levels in Patients With an Endoprosthesis
NCT04755140CI-TRIAL-00083769completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this research is to investigate whether patients who previously had endoprosthesis surgery experience memory, thinking, or heart problems. It will also help determine how often these problems occur.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Tumor | Bone Neoplasm | ALIAS | 0.90 |
| Cancer of Bone | Malignant Bone Neoplasm | ALIAS | 0.90 |
| Chemotherapy Effect | — | UNRESOLVED | — |
| Cognitive Decline | — | UNRESOLVED | — |
| Cognitive Impairment | — | UNRESOLVED | — |
| Heart Diseases | — | UNRESOLVED | — |
| Memory Problem | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood Test | Diagnostic Test | — | UNRESOLVED |
| Echocardiogram | Diagnostic Test | — | UNRESOLVED |
| Interviews | Behavioral | — | UNRESOLVED |
| Questionnaires | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Endoprosthesis
- description
- Patients with a endoprosthesis
- interventionNames
- Behavioral: Questionnaires
- Behavioral: Interviews
- Diagnostic Test: Blood Test
- Diagnostic Test: Echocardiogram
Primary outcomes (6)
- measure
- Echo - Left Ventricular Ejection Fraction
- timeFrame
- Echo's will be taken at baseline, 1 year, and 2 years
- description
- The echocardiogram will measure changes in LV ejection fraction as a percent.
- measure
- Echo - Left Ventricular Mass
- timeFrame
- Echo's will be taken at baseline, 1 year, and 2 years
- description
- The echocardiogram will measure changes in LV Mass in grams.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Patient has an endoprosthesis after extremity malignancy Exclusion Criteria: * Current fracture or infection around the endoprosthesis * Patient is pregnant
References
Publications (0)
Data not yet available
No reference posted for this study.