Clinical trial · Interventional
A Prospective Study of Surgical Treatment Strategies for Chordoma
NCT05707767CI-TRIAL-00068093unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Chordoma is a rare but locally invasive cancer that arises from the embryonic notochord. Total resection is challenging in mobile spine because of the complex anatomy and bone invasion.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chordoma of Spine | Spinal Chordoma | ALIAS | 0.90 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Resection surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Chordoma Patients
- description
- Chordoma Patients
- interventionNames
- Procedure: Resection surgery
Primary outcomes (1)
- measure
- Excision Extension
- timeFrame
- 1 week after surgery.
- description
- Clinical and radiographic assessments of excision extension of tumor.
Secondary outcomes (4)
- measure
- OS (Overall Survival)
- timeFrame
- 2 years
- description
- Overall Survival of patient underwent surgery.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Between the ages of 18 and 70 ys, * With a diagnosis of chordoma confirmed by pathology, * Undergone surgical treatment in our hospital, * Available for clinical follow-up and agree to long-term clinical follow-up and sign informed consent. Exclusion Criteria: * Suffer from other tumors, * Suffer from cardiovascular disease, cerebrovascular disease, or immune system disease.
References
Publications (5)
- RESULTWalcott BP, Nahed BV, Mohyeldin A, Coumans JV, Kahle KT, Ferreira MJ. Chordoma: current concepts, management, and future directions. Lancet Oncol. 2012 Feb;13(2):e69-76. doi: 10.1016/S1470-2045(11)70337-0. PMID 22300861
- RESULTWedekind MF, Widemann BC, Cote G. Chordoma: Current status, problems, and future directions. Curr Probl Cancer. 2021 Aug;45(4):100771. doi: 10.1016/j.currproblcancer.2021.100771. Epub 2021 Jul 1. PMID 34266694
- RESULTYeter HG, Kosemehmetoglu K, Soylemezoglu F. Poorly differentiated chordoma: review of 53 cases. APMIS. 2019 Sep;127(9):607-615. doi: 10.1111/apm.12978. PMID 31243811
- RESULTKolz JM, Wellings EP, Houdek MT, Clarke MJ, Yaszemski MJ, Rose PS. Surgical treatment of primary mobile spine chordoma. J Surg Oncol. 2021 Apr;123(5):1284-1291. doi: 10.1002/jso.26423. Epub 2021 Feb 10. PMID 33567141
- RESULTWilliams BJ, Raper DM, Godbout E, Bourne TD, Prevedello DM, Kassam AB, Park DM. Diagnosis and treatment of chordoma. J Natl Compr Canc Netw. 2013 Jun 1;11(6):726-31. doi: 10.6004/jnccn.2013.0089. PMID 23744869