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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
22 stopped studies mapped to Malignant Bone Neoplasm and descendants · 95% state a reason
Over the 22 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT05691478 | A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With… | Phase 2 / Phase 3 | suspended | Jan 20, 2023 | National Cancer Institute (NCI) | Other - Extend the observation period for current patients | Other (stated, no rule matched) |
| NCT06008483 | A Dose Finding Study to Treat Bone Tumor(s) | Phase 1 | terminated | Aug 23, 2023 | QSAM Therapeutics, Inc. | Change in development program indication | Other (stated, no rule matched) |
| NCT03420963 | Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and… | Phase 1 | terminated | Feb 5, 2018 | M.D. Anderson Cancer Center | \<75% participation | Other (stated, no rule matched) |
| NCT04410042 | Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing… | Phase 3 | terminated | Jun 1, 2020 | St. Jude Children's Research Hospital | Per sponsor | Other (stated, no rule matched) |
| NCT04740749 | Longevity, Functional Status and Quality of Life of the Compress® Compliant Pre-Stress…(Compress) | N/A | terminated | Feb 5, 2021 | Universitaire Ziekenhuizen KU Leuven | Masterthesis completed | Other (stated, no rule matched) |
| NCT03525392 | Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in… | Phase 1 | terminated | May 15, 2018 | Ipsen | Due to agreement to transfer rights for IPN01087 to an external partner, not due to safety concerns | Safety / toxicity |
| NCT04877587 | Gemcitabine With Ascorbate Including Adolescents | Early Phase 1 | withdrawn | May 7, 2021 | David Dickens | Unable to enroll | Enrollment / accrual |
| NCT05116800 | Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma | Phase 2 | withdrawn | Nov 11, 2021 | Brown University | IND withdrawn | Other (stated, no rule matched) |
| NCT04906876 | A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With… | Phase 2 | withdrawn | May 28, 2021 | Brown University | IND withdrawn | Other (stated, no rule matched) |
| NCT03468075 | Gemcitabine Plus Ascorbate for Sarcoma in Adults | Phase 2 | terminated | Mar 16, 2018 | Mohammed Milhem, MBBS | Stopping rules met | Other (stated, no rule matched) |
| NCT02199938 | Identification and Characterization of Molecular Markers in Musculoskeletal Tumors | — | terminated | Jul 25, 2014 | Balgrist University Hospital | Principal Investigator has left the Institution | Investigator |
| NCT02775799 | National Swiss Sarcoma Cohort Study(SwissSARCOS) | — | terminated | May 18, 2016 | Balgrist University Hospital | Principal Investigator has left the Institution | Investigator |
| NCT00960063 | A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment… | Phase 1 | terminated | Aug 17, 2009 | Merck Sharp & Dohme LLC | Study was terminated for business reasons. | Sponsor / business decision |
| NCT02443103 | Study Evaluating the Biologic Activity of Guanabenz in Bone Metastasis | N/A | terminated | May 13, 2015 | Kathy Miller | Slow accrual | Enrollment / accrual |
| NCT01313884 | Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings… | Phase 2 | terminated | Mar 14, 2011 | Stanford University | Study did not reach primary objective; study did not accrue enough patients. | Enrollment / accrual |
| NCT03002454 | Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v… | Phase 3 | terminated | Dec 23, 2016 | University of Manitoba | Altered biodistribution in investigational images versus standard images. | Other (stated, no rule matched) |
| NCT01541358 | Sodium Fluoride PET/CT for the Evaluation of Skeletal Cancer | N/A | terminated | Feb 29, 2012 | Stanford University | Low accrual and no funding | Enrollment / accrual |
| NCT01163539 | Cyberknife Radiosurgery and Quality of Life | — | terminated | Jul 15, 2010 | Stanford University | not stated | Not stated |
| NCT01795430 | Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed… | N/A | withdrawn | Feb 20, 2013 | City of Hope Medical Center | No participants enrolled. | Enrollment / accrual |
| NCT00334984 | Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma | N/A | withdrawn | Jun 8, 2006 | Children's Oncology Group | Withdrawn due to inability to reach an acceptable agreement with industry sponsor | Other (stated, no rule matched) |
| NCT00632294 | Retrospective Study of the Biomechanical Properties of Large Allografts | — | terminated | Mar 10, 2008 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT00127387 | Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia | Phase 2 / Phase 3 | terminated | Aug 5, 2005 | The University of Texas Health Science Center at San Antonio | PI moved to Oregon | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 11 hours agoSource updated Sep 29, 2026source: clinicaltrials