Subtype
Malignant Bone Neoplasm
CI-CAN-00001109Explore in graph →
38 active trials4 approved drugs8 evidence items
- NCIt
- C4016
Loading cancer entity…
Subtype
CI-CAN-00001109Explore in graph →
Clinical trials
152 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (18)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05395741 | Regorafenib in Patients With Refractory Primary Bone Tumors(Regbone) | completed | Phase 1 / Phase 2 | 30 | Institute of Mother and Child, Warsaw, PolandOTHER | 1 | Aug 21, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH |
| 3 |
| Jun 17, 2026 |
| clinicaltrials |
| NCT03462316 | NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma | completed | Phase 1 | 2 | Sun Yat-sen UniversityOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT04650594 | Functional Outcomes of Knee Protheses for Malignant Tumours of Bone(ISOMUTAR) | completed | N/A | 9 | University Hospital, LilleOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT02415816 | Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas | completed | N/A | 98 | St. Jude Children's Research HospitalOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT05746429 | Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer | completed | N/A | 68 | St. Jude Children's Research HospitalOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT01231906 | Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma | completed | Phase 3 | 642 | Children's Oncology GroupNETWORK | 6 | Jan 23, 2026 | clinicaltrials |
| NCT06562673 | Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma(IACE-OS) | completed | Phase 1 / Phase 2 | 10 | Shanghai 6th People's HospitalOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT00592293 | Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas | completed | N/A | 70 | Massachusetts General HospitalOTHER | 1 | Jul 3, 2025 | clinicaltrials |
| NCT05131815 | The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors | completed | N/A | 8 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT03154190 | Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer | completed | N/A | 128 | Stanford UniversityOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT04755140 | Endoprosthesis Metal Toxicity Study | completed | — | 20 | Mayo ClinicOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT04963517 | Exercise Intervention for Bone Tumor Patients(proGAIT) | completed | Phase 2 / Phase 3 | 11 | Universität Duisburg-EssenOTHER | 1 | Dec 6, 2024 | clinicaltrials |
| NCT03277924 | Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas(ImmunoSarc) | completed | Phase 1 / Phase 2 | 197 | Grupo Espanol de Investigacion en SarcomasOTHER | 3 | Aug 13, 2024 | clinicaltrials |
| NCT01803152 | Dendritic Cell Vaccine for Children and Adults With Sarcoma | completed | Phase 1 | 19 | Macarena De La Fuente, MDOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT04296617 | Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors | completed | — | 36 | Mayo ClinicOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT00019630 | Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00020267 | Vaccine Therapy in Treating Patients With Metastatic Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT04310410 | Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis(PRE-FURTHER) | completed | Phase 1 / Phase 2 | 10 | UMC UtrechtOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT05024253 | Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements. | completed | Phase 3 | 48 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT02384473 | Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma | completed | Early Phase 1 | 25 | University of Southern CaliforniaOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06202599 | Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' Resistance | completed | — | 124 | Peking University People's HospitalOTHER | 1 | Jan 17, 2024 | clinicaltrials |
| NCT01336803 | Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI(Osteosarcoma) | completed | Phase 2 | 32 | Heike E Daldrup-LinkOTHER | 1 | Dec 27, 2023 | clinicaltrials |
| NCT06153576 | The Value of Systematic Biopsies During Vertebroplasty for the Treatment of Osteoporotic Vertebral Fractures | completed | — | 1,120 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Dec 11, 2023 | clinicaltrials |
| NCT04788147 | Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X)(BIOGUIDE-X) | completed | N/A | 30 | RefleXion MedicalINDUSTRY | 1 | Oct 31, 2023 | clinicaltrials |
| NCT02500797 | Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery | completed | Phase 2 | 164 | National Cancer Institute (NCI)NIH | 1 | Oct 17, 2023 | clinicaltrials |
| NCT00667342 | A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma | completed | Phase 2 | 43 | St. Jude Children's Research HospitalOTHER | 1 | Aug 7, 2023 | clinicaltrials |
| NCT02821507 | Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma | completed | Phase 2 | 70 | Leiden University Medical CenterOTHER | 2 | Apr 20, 2022 | clinicaltrials |
| NCT02323295 | Effect of High Doses of Radiation on Bone Structure and Metabolism | completed | N/A | 12 | Massachusetts General HospitalOTHER | 1 | Dec 7, 2021 | clinicaltrials |
| NCT03284320 | Retrospective Study in Sarcoma Patients(ReTraSarc) | completed | — | 514 | University Medicine GreifswaldOTHER | 1 | Nov 15, 2021 | clinicaltrials |
| NCT03768076 | an Istitution Experience on Parosteal OsTeosarcoma | completed | — | 220 | Istituto Ortopedico RizzoliOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT00525057 | Dalteparin in Preventing DVT in Participants With Cancer | completed | N/A | 65 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT02520128 | A Study of IMRT in Primary Bone and Soft Tissue Sarcoma(IMRiS) | completed | N/A | 191 | University College, LondonOTHER | 2 | Dec 2, 2020 | clinicaltrials |
| NCT02192333 | Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors | completed | N/A | 390 | Fred Hutchinson Cancer CenterOTHER | 1 | Oct 9, 2020 | clinicaltrials |
| NCT02301039 | SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas | completed | Phase 2 | 144 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Sep 29, 2020 | clinicaltrials |
| NCT01047878 | Genomic Analysis of Pediatric Bone Tumors | completed | — | 163 | Stanford UniversityOTHER | 1 | Jul 28, 2020 | clinicaltrials |
| NCT03968471 | Chemotherapy-induced Necrosis in Ewing Sarcoma | completed | — | 474 | Istituto Ortopedico RizzoliOTHER | 1 | Jan 22, 2020 | clinicaltrials |
| NCT01553539 | Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery | completed | Phase 2 | 20 | Wake Forest University Health SciencesOTHER | 1 | Jul 5, 2018 | clinicaltrials |
| NCT00931931 | HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors | completed | Phase 1 | 18 | Timothy CripeOTHER | 1 | Mar 21, 2018 | clinicaltrials |
| NCT00674193 | Evaluating Dactinomycin and Vincristine in Young Patients With Cancer | completed | — | 158 | Children's Oncology GroupNETWORK | 3 | May 17, 2017 | clinicaltrials |
| NCT00450736 | Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery | completed | Phase 1 | 3 | University of MiamiOTHER | 1 | Dec 15, 2016 | clinicaltrials |
| NCT00720174 | Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | May 17, 2016 | clinicaltrials |
| NCT01085565 | Focused Ultrasound Surgery in the Treatment of Pain Resulting From Metastatic Bone Tumors With the ExAblate 2100 Conformal Bone System | completed | Phase 2 | 50 | InSightecINDUSTRY | 1 | Mar 8, 2016 | clinicaltrials |
| NCT00474994 | Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas | completed | Phase 2 | 53 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 20, 2016 | clinicaltrials |
| NCT01674101 | Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy | completed | N/A | 20 | St. Jude Children's Research HospitalOTHER | 1 | Dec 4, 2015 | clinicaltrials |
| NCT01135849 | B-Receptor Signaling in Cardiomyopathy | completed | — | 99 | Daniel BernsteinOTHER | 1 | Nov 17, 2015 | clinicaltrials |
Data updated 22 days agoSource updated Aug 21, 2026source: clinicaltrials