Subtype
Genitourinary System Carcinoma
CI-CAN-00000925Explore in graph →
1,498 active trials44 approved drugs143 evidence items
- NCIt
- C164141
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Subtype
CI-CAN-00000925Explore in graph →
Genomics
108 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
333 cases with simple somatic mutation data · 333 cases total · 2026-01-16 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SPOP |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 37 |
| 333 |
| 11.1% |
| cbioportal |
| 2 | TTN | Ssm | 37 | 333 | 11.1% | cbioportal |
| 3 | TP53 | Ssm | 23 | 333 | 6.9% | cbioportal |
| 4 | MUC16 | Ssm | 20 | 333 | 6% | cbioportal |
| 5 | MUC17 | Ssm | 17 | 333 | 5.1% | cbioportal |
| 6 | SPTA1 | Ssm | 15 | 333 | 4.5% | cbioportal |
| 8 | FOXA1 | Ssm | 13 | 333 | 3.9% | cbioportal |
| 7 | ATM | Ssm | 13 | 333 | 3.9% | cbioportal |
| 9 | KMT2C | Ssm | 13 | 333 | 3.9% | cbioportal |
| 12 | LRP1B | Ssm | 12 | 333 | 3.6% | cbioportal |
| 11 | CSMD3 | Ssm | 12 | 333 | 3.6% | cbioportal |
| 10 | AHNAK2 | Ssm | 12 | 333 | 3.6% | cbioportal |
| 13 | KMT2D | Ssm | 11 | 333 | 3.3% | cbioportal |
| 14 | OBSCN | Ssm | 11 | 333 | 3.3% | cbioportal |
| 16 | FAT3 | Ssm | 10 | 333 | 3% | cbioportal |
| 18 | RP1 | Ssm | 10 | 333 | 3% | cbioportal |
| 15 | AHNAK | Ssm | 10 | 333 | 3% | cbioportal |
| 17 | HMCN1 | Ssm | 10 | 333 | 3% | cbioportal |
| 22 | PTEN | Ssm | 9 | 333 | 2.7% | cbioportal |
| 19 | BRCA2 | Ssm | 9 | 333 | 2.7% | cbioportal |
| 20 | DCHS2 | Ssm | 9 | 333 | 2.7% | cbioportal |
| 21 | FLG2 | Ssm | 9 | 333 | 2.7% | cbioportal |
| 23 | ADGRB3 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 32 | SYNE1 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 30 | PCDH18 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 24 | ADGRV1 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 29 | MACF1 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 31 | RYR2 | Ssm | 8 | 333 | 2.4% | cbioportal |
| 33 | USH2A | Ssm | 8 | 333 | 2.4% | cbioportal |
| 28 | FLG | Ssm | 8 | 333 | 2.4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-16