Subtype
Genitourinary System Carcinoma
CI-CAN-00000925Explore in graph →
1,498 active trials44 approved drugs143 evidence items
- NCIt
- C164141
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Subtype
CI-CAN-00000925Explore in graph →
Genomics
108 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
559 cases with simple somatic mutation data · 560 cases total · Data Release 46.0 · mapped to Endometrial Carcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| PTEN |
| Ssm |
| 418 |
| 559 |
| 74.8% |
| gdc |
| 2 | PIK3CA | Ssm | 349 | 559 | 62.4% | gdc |
| 3 | ARID1A | Ssm | 319 | 559 | 57.1% | gdc |
| 4 | TTN | Ssm | 297 | 559 | 53.1% | gdc |
| 5 | OBSCN | Ssm | 296 | 559 | 53% | gdc |
| 6 | RYR2 | Ssm | 291 | 559 | 52.1% | gdc |
| 7 | ASH1L | Ssm | 289 | 559 | 51.7% | gdc |
| 8 | USH2A | Ssm | 286 | 559 | 51.2% | gdc |
| 9 | FLG | Ssm | 283 | 559 | 50.6% | gdc |
| 10 | CACNA1E | Ssm | 281 | 559 | 50.3% | gdc |
| 11 | HMCN1 | Ssm | 278 | 559 | 49.7% | gdc |
| 14 | CEP350 | Ssm | 277 | 559 | 49.6% | gdc |
| 13 | HRNR | Ssm | 277 | 559 | 49.6% | gdc |
| 12 | CSMD3 | Ssm | 277 | 559 | 49.6% | gdc |
| 15 | CTCF | Ssm | 276 | 559 | 49.4% | gdc |
| 18 | ZFHX3 | Ssm | 275 | 559 | 49.2% | gdc |
| 17 | ASPM | Ssm | 275 | 559 | 49.2% | gdc |
| 16 | GON4L | Ssm | 275 | 559 | 49.2% | gdc |
| 19 | NFASC | Ssm | 271 | 559 | 48.5% | gdc |
| 20 | CSMD1 | Ssm | 270 | 559 | 48.3% | gdc |
| 22 | SPTA1 | Ssm | 269 | 559 | 48.1% | gdc |
| 21 | PDE4DIP | Ssm | 269 | 559 | 48.1% | gdc |
| 23 | INSRR | Ssm | 269 | 559 | 48.1% | gdc |
| 24 | SETDB1 | Ssm | 267 | 559 | 47.8% | gdc |
| 26 | MUC16 | Ssm | 266 | 559 | 47.6% | gdc |
| 27 | COPA | Ssm | 266 | 559 | 47.6% | gdc |
| 25 | F5 | Ssm | 266 | 559 | 47.6% | gdc |
| 29 | ARHGEF2 | Ssm | 265 | 559 | 47.4% | gdc |
| 28 | PRRC2C | Ssm | 265 | 559 | 47.4% | gdc |
| 30 | LYST | Ssm | 264 | 559 | 47.2% | gdc |
Data updated 22 days agoSource updated Data Release 46.0