Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

3 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Ewing Sarcoma (Institut Curie, Cancer Discov 2014) es_iocurie_2014Institut Curie

112 cases with simple somatic mutation data · 115 cases total · 2026-01-07 · mapped to Ewing Sarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	STAG2	Ssm	18	112	16.1%	cbioportal
2	TP53	Ssm	8	112	7.1%	cbioportal
4	TTN	Ssm	5	112	4.5%	cbioportal
3	CSMD1	Ssm	5	112	4.5%	cbioportal
5	EZH2	Ssm	3	112	2.7%	cbioportal
7	RYR2	Ssm	3	112	2.7%	cbioportal
6	MACF1	Ssm	3	112	2.7%	cbioportal
22	DPP10

Data updated 22 days agoSource updated 2026-01-07

Ewing Sarcoma (MSK, Cancer Research 2024) es_dsrct_msk_2023MSK

290 cases with simple somatic mutation data · 290 cases total · 2026-02-14 · mapped to Ewing Sarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm

Pediatric Ewing Sarcoma (DFCI, Cancer Discov 2014) es_dfarber_broad_2014DFCI

107 cases with simple somatic mutation data · 107 cases total · 2026-01-07 · mapped to Ewing Sarcoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TTN	Ssm

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.