Gene
COP1
COP1 E3 ubiquitin ligase
Explore in graph →CI-GENE-00041927HGNC:17440 ENSG00000143207 NCBI 64326 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (73)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 8 | 22 | 36.4% | 69 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, Science 2015) nsclc_mskcc_2015 | Lung Non-Small Cell Carcinoma | Ssm | 2 | 16 | 12.5% | 198 | cbioportal |
| Endometrial and Ovarian Cancer (MSK, Nature Medicine 2024) ucec_msk_2024 | unmapped | Ssm | 3 | 33 | 9.1% | 130 | cbioportal |
| Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSK, Neuro Oncol 2017) odg_msk_2017 | Diffuse Glioma | Ssm | 2 | 22 | 9.1% | 22 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.