Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
528 cases with simple somatic mutation data · 528 cases total · Data Release 46.0 · mapped to Head and Neck Squamous Cell Carcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 |
| TP53 |
| Ssm |
| 392 |
| 528 |
| 74.2% |
| gdc |
| 2 | PIK3CA | Ssm | 390 | 528 | 73.9% | gdc |
| 3 | CSMD3 | Ssm | 387 | 528 | 73.3% | gdc |
| 4 | CDKN2A | Ssm | 384 | 528 | 72.7% | gdc |
| 5 | FAM135B | Ssm | 383 | 528 | 72.5% | gdc |
| 6 | PLD1 | Ssm | 377 | 528 | 71.4% | gdc |
| 7 | COL22A1 | Ssm | 376 | 528 | 71.2% | gdc |
| 8 | CLDN16 | Ssm | 374 | 528 | 70.8% | gdc |
| 13 | TP63 | Ssm | 373 | 528 | 70.6% | gdc |
| 9 | BCL6 | Ssm | 373 | 528 | 70.6% | gdc |
| 11 | PKHD1L1 | Ssm | 373 | 528 | 70.6% | gdc |
| 10 | MB21D2 | Ssm | 373 | 528 | 70.6% | gdc |
| 12 | SI | Ssm | 373 | 528 | 70.6% | gdc |
| 14 | IL1RAP | Ssm | 373 | 528 | 70.6% | gdc |
| 16 | RUBCN | Ssm | 372 | 528 | 70.5% | gdc |
| 15 | EIF4G1 | Ssm | 372 | 528 | 70.5% | gdc |
| 17 | MUC4 | Ssm | 372 | 528 | 70.5% | gdc |
| 19 | SPATA16 | Ssm | 372 | 528 | 70.5% | gdc |
| 20 | OSTN | Ssm | 372 | 528 | 70.5% | gdc |
| 18 | COL14A1 | Ssm | 372 | 528 | 70.5% | gdc |
| 21 | ADCY8 | Ssm | 371 | 528 | 70.3% | gdc |
| 26 | CCDC50 | Ssm | 371 | 528 | 70.3% | gdc |
| 29 | NLGN1 | Ssm | 371 | 528 | 70.3% | gdc |
| 28 | FER1L6 | Ssm | 371 | 528 | 70.3% | gdc |
| 22 | FGF12 | Ssm | 371 | 528 | 70.3% | gdc |
| 27 | SLC7A14 | Ssm | 371 | 528 | 70.3% | gdc |
| 23 | BDH1 | Ssm | 371 | 528 | 70.3% | gdc |
| 25 | LPP | Ssm | 371 | 528 | 70.3% | gdc |
| 30 | PLEC | Ssm | 371 | 528 | 70.3% | gdc |
| 24 | MELTF | Ssm | 371 | 528 | 70.3% | gdc |
Data updated 22 days agoSource updated Data Release 46.0