Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
30 cases with simple somatic mutation data · 61 cases total · 2026-01-16 · mapped to Colorectal Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 20 |
| 30 |
| 66.7% |
| cbioportal |
| 2 | MUC16 | Ssm | 17 | 30 | 56.7% | cbioportal |
| 3 | PCLO | Ssm | 17 | 30 | 56.7% | cbioportal |
| 6 | SYNE1 | Ssm | 16 | 30 | 53.3% | cbioportal |
| 5 | MUC19 | Ssm | 16 | 30 | 53.3% | cbioportal |
| 4 | MUC17 | Ssm | 16 | 30 | 53.3% | cbioportal |
| 8 | FLG | Ssm | 15 | 30 | 50% | cbioportal |
| 7 | APC | Ssm | 15 | 30 | 50% | cbioportal |
| 10 | RNF213 | Ssm | 14 | 30 | 46.7% | cbioportal |
| 9 | FSIP2 | Ssm | 14 | 30 | 46.7% | cbioportal |
| 20 | MUC4 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 15 | HECTD4 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 22 | TENM2 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 21 | PRRC2C | Ssm | 13 | 30 | 43.3% | cbioportal |
| 19 | MUC12 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 14 | DNAH5 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 11 | CHD7 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 13 | DNAH10 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 17 | LAMA3 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 18 | MKI67 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 16 | HMCN1 | Ssm | 13 | 30 | 43.3% | cbioportal |
| 12 | CUBN | Ssm | 13 | 30 | 43.3% | cbioportal |
| 24 | KMT2A | Ssm | 12 | 30 | 40% | cbioportal |
| 23 | CEP350 | Ssm | 12 | 30 | 40% | cbioportal |
| 27 | MACF1 | Ssm | 12 | 30 | 40% | cbioportal |
| 26 | LRP2 | Ssm | 12 | 30 | 40% | cbioportal |
| 25 | KMT2C | Ssm | 12 | 30 | 40% | cbioportal |
| 30 | UBR5 | Ssm | 12 | 30 | 40% | cbioportal |
| 28 | OBSCN | Ssm | 12 | 30 | 40% | cbioportal |
| 29 | POGZ | Ssm | 12 | 30 | 40% | cbioportal |
Data updated 22 days agoSource updated 2026-01-16