Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
536 cases with simple somatic mutation data · 537 cases total · Data Release 46.0 · mapped to Clear Cell Renal Cell Carcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| VHL |
| Ssm |
| 463 |
| 536 |
| 86.4% |
| gdc |
| 2 | PBRM1 | Ssm | 456 | 536 | 85.1% | gdc |
| 3 | BAP1 | Ssm | 451 | 536 | 84.1% | gdc |
| 4 | PLXNB1 | Ssm | 450 | 536 | 84% | gdc |
| 6 | GLB1 | Ssm | 450 | 536 | 84% | gdc |
| 5 | COL7A1 | Ssm | 450 | 536 | 84% | gdc |
| 18 | PFKFB4 | Ssm | 449 | 536 | 83.8% | gdc |
| 26 | IP6K2 | Ssm | 449 | 536 | 83.8% | gdc |
| 10 | PRKAR2A | Ssm | 449 | 536 | 83.8% | gdc |
| 12 | PTH1R | Ssm | 449 | 536 | 83.8% | gdc |
| 25 | TMA7 | Ssm | 449 | 536 | 83.8% | gdc |
| 27 | TMEM89 | Ssm | 449 | 536 | 83.8% | gdc |
| 8 | CDC25A | Ssm | 449 | 536 | 83.8% | gdc |
| 7 | TREX1 | Ssm | 449 | 536 | 83.8% | gdc |
| 15 | UCN2 | Ssm | 449 | 536 | 83.8% | gdc |
| 11 | UQCRC1 | Ssm | 449 | 536 | 83.8% | gdc |
| 21 | NCKIPSD | Ssm | 449 | 536 | 83.8% | gdc |
| 9 | CELSR3 | Ssm | 449 | 536 | 83.8% | gdc |
| 23 | VIPR1 | Ssm | 449 | 536 | 83.8% | gdc |
| 19 | FBXW12 | Ssm | 449 | 536 | 83.8% | gdc |
| 17 | CCDC51 | Ssm | 449 | 536 | 83.8% | gdc |
| 20 | SCN5A | Ssm | 449 | 536 | 83.8% | gdc |
| 14 | SETD2 | Ssm | 449 | 536 | 83.8% | gdc |
| 16 | SHISA5 | Ssm | 449 | 536 | 83.8% | gdc |
| 13 | SLC26A6 | Ssm | 449 | 536 | 83.8% | gdc |
| 22 | HHATL | Ssm | 449 | 536 | 83.8% | gdc |
| 24 | ATRIP | Ssm | 449 | 536 | 83.8% | gdc |
| 31 | GPX1 | Ssm | 448 | 536 | 83.6% | gdc |
| 67 | IHO1 | Ssm | 448 | 536 | 83.6% | gdc |
| 71 | IQCF1 | Ssm | 448 | 536 | 83.6% | gdc |
Data updated 22 days agoSource updated Data Release 46.0