Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
65 cases with simple somatic mutation data · 65 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 35 |
| 65 |
| 53.8% |
| cbioportal |
| 2 | PIK3CA | Ssm | 7 | 65 | 10.8% | cbioportal |
| 3 | MYO3A | Ssm | 6 | 65 | 9.2% | cbioportal |
| 4 | USH2A | Ssm | 6 | 65 | 9.2% | cbioportal |
| 5 | PTEN | Ssm | 5 | 65 | 7.7% | cbioportal |
| 9 | LRP2 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 13 | TTN | Ssm | 4 | 65 | 6.2% | cbioportal |
| 6 | ADGRG4 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 14 | UBR5 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 11 | RB1 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 15 | ZNF142 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 8 | COL6A3 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 12 | SYNE1 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 10 | MDN1 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 7 | ATR | Ssm | 4 | 65 | 6.2% | cbioportal |
| 23 | EMSY | Ssm | 3 | 65 | 4.6% | cbioportal |
| 17 | ARHGAP5 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 21 | DLG5 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 24 | FMN2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 26 | HECW1 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 16 | ADGRL2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 30 | MUC17 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 38 | SMG5 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 39 | SPHKAP | Ssm | 3 | 65 | 4.6% | cbioportal |
| 40 | SYNE2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 41 | TASOR2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 42 | TDO2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 43 | TSHZ3 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 19 | CELSR1 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 45 | USF3 | Ssm | 3 | 65 | 4.6% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05