Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
431 cases with simple somatic mutation data · 443 cases total · 2026-01-14 · mapped to Gastric Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm | 221 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 431 |
| 51.3% |
| cbioportal |
| 2 | TP53 | Ssm | 198 | 431 | 45.9% | cbioportal |
| 3 | MUC16 | Ssm | 135 | 431 | 31.3% | cbioportal |
| 4 | ARID1A | Ssm | 116 | 431 | 26.9% | cbioportal |
| 5 | LRP1B | Ssm | 115 | 431 | 26.7% | cbioportal |
| 6 | CSMD3 | Ssm | 102 | 431 | 23.7% | cbioportal |
| 7 | SYNE1 | Ssm | 102 | 431 | 23.7% | cbioportal |
| 8 | FAT4 | Ssm | 92 | 431 | 21.3% | cbioportal |
| 9 | FLG | Ssm | 85 | 431 | 19.7% | cbioportal |
| 10 | PCLO | Ssm | 81 | 431 | 18.8% | cbioportal |
| 11 | HMCN1 | Ssm | 80 | 431 | 18.6% | cbioportal |
| 12 | ACVR2A | Ssm | 77 | 431 | 17.9% | cbioportal |
| 13 | ZFHX4 | Ssm | 77 | 431 | 17.9% | cbioportal |
| 14 | DNAH5 | Ssm | 76 | 431 | 17.6% | cbioportal |
| 16 | SPTA1 | Ssm | 74 | 431 | 17.2% | cbioportal |
| 15 | OBSCN | Ssm | 74 | 431 | 17.2% | cbioportal |
| 17 | RYR2 | Ssm | 73 | 431 | 16.9% | cbioportal |
| 18 | CSMD1 | Ssm | 71 | 431 | 16.5% | cbioportal |
| 19 | FAT3 | Ssm | 71 | 431 | 16.5% | cbioportal |
| 20 | KMT2D | Ssm | 68 | 431 | 15.8% | cbioportal |
| 21 | PIK3CA | Ssm | 67 | 431 | 15.5% | cbioportal |
| 22 | DST | Ssm | 66 | 431 | 15.3% | cbioportal |
| 23 | SACS | Ssm | 65 | 431 | 15.1% | cbioportal |
| 25 | PLEC | Ssm | 62 | 431 | 14.4% | cbioportal |
| 24 | PCDH15 | Ssm | 62 | 431 | 14.4% | cbioportal |
| 26 | DMD | Ssm | 61 | 431 | 14.2% | cbioportal |
| 27 | LRRK2 | Ssm | 60 | 431 | 13.9% | cbioportal |
| 29 | UBR5 | Ssm | 59 | 431 | 13.7% | cbioportal |
| 28 | SYNE2 | Ssm | 59 | 431 | 13.7% | cbioportal |
| 31 | CUBN | Ssm | 58 | 431 | 13.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-14