Cancer Family
Epithelial Neoplasm
CI-CAN-00000016Explore in graph →
Non-malignant7,525 active trials118 approved drugs1,152 evidence items
- NCIt
- C3709
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Cancer Family
CI-CAN-00000016Explore in graph →
Genomics
314 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
216 cases with simple somatic mutation data · 216 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 84 |
| 216 |
| 38.9% |
| cbioportal |
| 2 | PIK3CA | Ssm | 66 | 216 | 30.6% | cbioportal |
| 3 | TTN | Ssm | 40 | 216 | 18.5% | cbioportal |
| 4 | GATA3 | Ssm | 26 | 216 | 12% | cbioportal |
| 5 | ESR1 | Ssm | 22 | 216 | 10.2% | cbioportal |
| 6 | RYR2 | Ssm | 20 | 216 | 9.3% | cbioportal |
| 7 | MAP3K1 | Ssm | 18 | 216 | 8.3% | cbioportal |
| 8 | CDH1 | Ssm | 16 | 216 | 7.4% | cbioportal |
| 9 | FSIP2 | Ssm | 16 | 216 | 7.4% | cbioportal |
| 13 | USH2A | Ssm | 15 | 216 | 6.9% | cbioportal |
| 11 | HMCN1 | Ssm | 15 | 216 | 6.9% | cbioportal |
| 12 | OBSCN | Ssm | 15 | 216 | 6.9% | cbioportal |
| 10 | FRAS1 | Ssm | 15 | 216 | 6.9% | cbioportal |
| 16 | RYR3 | Ssm | 14 | 216 | 6.5% | cbioportal |
| 17 | SYNE1 | Ssm | 14 | 216 | 6.5% | cbioportal |
| 14 | KMT2C | Ssm | 14 | 216 | 6.5% | cbioportal |
| 15 | MUC16 | Ssm | 14 | 216 | 6.5% | cbioportal |
| 21 | FLG | Ssm | 13 | 216 | 6% | cbioportal |
| 22 | NEB | Ssm | 13 | 216 | 6% | cbioportal |
| 20 | DNAH9 | Ssm | 13 | 216 | 6% | cbioportal |
| 19 | DNAH6 | Ssm | 13 | 216 | 6% | cbioportal |
| 23 | PKHD1L1 | Ssm | 13 | 216 | 6% | cbioportal |
| 18 | DMD | Ssm | 13 | 216 | 6% | cbioportal |
| 25 | CACNA1E | Ssm | 12 | 216 | 5.6% | cbioportal |
| 29 | TENM3 | Ssm | 12 | 216 | 5.6% | cbioportal |
| 27 | PCLO | Ssm | 12 | 216 | 5.6% | cbioportal |
| 30 | XIRP2 | Ssm | 12 | 216 | 5.6% | cbioportal |
| 24 | ANK3 | Ssm | 12 | 216 | 5.6% | cbioportal |
| 26 | NF1 | Ssm | 12 | 216 | 5.6% | cbioportal |
| 28 | RYR1 | Ssm | 12 | 216 | 5.6% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05