Gene
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
Explore in graph →CI-GENE-00044548HGNC:3296 ENSG00000114867 NCBI 1981 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (15)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Squamous Cell Carcinoma TCGA-LUSC | Lung Squamous Cell Carcinoma | Ssm | 442 | 504 | 87.7% | 30 | gdc |
| Small-Cell Lung Cancer (Multi-Institute, Cancer Cell 2017) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.