Subtype
Digestive System Adenocarcinoma
CI-CAN-00002525Explore in graph →
1,373 active trials24 approved drugs77 evidence items
- NCIt
- C210140
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Subtype
CI-CAN-00002525Explore in graph →
Genomics
73 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
19 cases with simple somatic mutation data · 19 cases total · 2026-01-07 · mapped to Hepatocellular Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TERT |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 7 |
| 19 |
| 36.8% |
| cbioportal |
| 3 | HNF1A | Ssm | 3 | 19 | 15.8% | cbioportal |
| 2 | CTNNB1 | Ssm | 3 | 19 | 15.8% | cbioportal |
| 4 | TP53 | Ssm | 3 | 19 | 15.8% | cbioportal |
| 6 | PIK3CA | Ssm | 2 | 19 | 10.5% | cbioportal |
| 5 | APC | Ssm | 2 | 19 | 10.5% | cbioportal |
| 12 | BRCA1 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 13 | BTK | Ssm | 1 | 19 | 5.3% | cbioportal |
| 14 | CDK12 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 15 | CDKN1A | Ssm | 1 | 19 | 5.3% | cbioportal |
| 16 | CDKN1B | Ssm | 1 | 19 | 5.3% | cbioportal |
| 17 | CTCF | Ssm | 1 | 19 | 5.3% | cbioportal |
| 18 | CUL3 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 19 | DNMT3B | Ssm | 1 | 19 | 5.3% | cbioportal |
| 20 | EED | Ssm | 1 | 19 | 5.3% | cbioportal |
| 21 | EP300 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 22 | ERG | Ssm | 1 | 19 | 5.3% | cbioportal |
| 23 | FAT1 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 24 | GNAS | Ssm | 1 | 19 | 5.3% | cbioportal |
| 25 | HGF | Ssm | 1 | 19 | 5.3% | cbioportal |
| 26 | KDM6A | Ssm | 1 | 19 | 5.3% | cbioportal |
| 27 | KEAP1 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 28 | KMT2C | Ssm | 1 | 19 | 5.3% | cbioportal |
| 29 | KMT2D | Ssm | 1 | 19 | 5.3% | cbioportal |
| 30 | LATS1 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 31 | MSH6 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 32 | NOTCH3 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 33 | NSD1 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 34 | PAK5 | Ssm | 1 | 19 | 5.3% | cbioportal |
| 35 | PAX5 | Ssm | 1 | 19 | 5.3% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07