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Connective and Soft Tissue Neoplasm — Research · CancerIndex

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Connective and Soft Tissue Neoplasm

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Connective and Soft Tissue Neoplasm

CI-CAN-00000010Explore in graph →

Non-malignant848 active trials17 approved drugs339 evidence items

NCIt: C3810
MeSH: D018204

Overview
Statistics
Survival
Genomics24
Variants & evidence339
Drugs43
Trials3877
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

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Trials tab
Methodology: publication counts

Literature

Linked publications (225)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 176–200 of 225 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Novel fusion sarcomas including targetable NTRK and ALK.
· Ann Diagn Pathol · 2021 · PMID 34464935 · validated civic_curation pubmed
Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor.
· Cancer Res · 1994 · PMID 8187063 · validated civic_curation pubmed
Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISH.
· Genes Chromosomes Cancer · 2016 · PMID 26690869 · validated civic_curation pubmed
Immunophenotype-Genotype Correlations in Clear Cell Sarcoma of Kidney-An Evaluation of Diagnostic Ancillary Studies.
· Pediatr Dev Pathol · 2020 · PMID 32364435 · validated civic_curation pubmed
Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story.
· J Pathol · 2016 · PMID 27000436 · validated civic_curation pubmed
FOS-ANKH and FOS-RUNX2 Fusion Genes in Osteoblastoma.
· Cancer Genomics Proteomics · 2020 · PMID 32108038 · validated civic_curation pubmed
Clear cell sarcomas of the kidney are characterised by BCOR gene abnormalities, including exon 15 internal tandem duplications and BCOR-CCNB3 gene fusion.
· Histopathology · 2018 · PMID 28833375 · validated civic_curation

Showing 176–200 of 225 publications

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BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney.

· Pediatr Blood Cancer · 2020 · PMID 31876361 · validated civic_curation pubmed

Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues.

· Am J Surg Pathol · 2017 · PMID 28817404 · validated civic_curation pubmed

Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma.

· BMC Cancer · 2016 · PMID 27418251 · validated civic_curation pubmed

NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker.

· Mod Pathol · 2020 · PMID 32327700 · validated civic_curation pubmed

Gastroblastoma mimics the embryonic mesenchyme of the foregut: a case report.

· Diagn Pathol · 2023 · PMID 36803776 · validated civic_curation pubmed

Gastroblastoma in old age.

· Histopathology · 2019 · PMID 31287169 · validated civic_curation pubmed

EML4-NTRK3 Fusion Cervical Sarcoma: A Case Report and Literature Review.

· Front Med (Lausanne) · 2022 · PMID 35572973 · validated civic_curation pubmed

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.

· Clin Cancer Res · 2014 · PMID 25239608 · validated civic_curation pubmed

Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors.

· Clin Cancer Res · 2012 · PMID 22745105 · validated civic_curation pubmed

Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 and p16ink4 mRNA.

· Oncotarget · 2015 · PMID 26528855 · validated civic_curation pubmed

Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.

· Cancer Cell · 2014 · PMID 25453902 · validated civic_curation pubmed

The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice.

· Oncogene · 2000 · PMID 10828883 · validated civic_curation pubmed

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

· Gastroenterology · 2003 · PMID 12949711 · validated civic_curation pubmed

Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma.

· Br J Cancer · 2015 · PMID 26291055 · validated civic_curation pubmed

KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors.

· Cancer Res · 2009 · PMID 19723655 · validated civic_curation pubmed

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.

· Clin Cancer Res · 2015 · PMID 26179511 · validated civic_curation pubmed

BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction.

· Cell Rep · 2014 · PMID 24373973 · validated civic_curation pubmed

Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.

· Cancer Res · 2009 · PMID 19366796 · validated civic_curation pubmed