Publication
Novel fusion sarcomas including targetable NTRK and ALK.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerSarcomacivic_curation1.00
- geneNTRK2civic_curation1.00
- variantNTRK2 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 34464935
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| ALK Fusion1 | ||||||||
| Crizotinib | Sarcoma | Predictive | C | Supports Sensitivity Response | 4 | submitted | EID11032Case study of a 2-year-old male with a slowly enlarging mass and gradual loss of function in right hand. First considered to be a vascular malformation. Tumor involved soft tissue spaces around a… (full text at CIViC) PMID 34464935 · Chen et al., 2021 · Open in CIViC | civic |
| NTRK2 Fusion1 | ||||||||
| (oncogenic) | Sarcoma | Oncogenic | C | Supports Oncogenicity | 2 | accepted | EID10362In a further investigation of non-traditional sarcoma cases, a 41-year-old man was thought to have a malignant peripheral nerve sheath tumor (MPNST) in the neck and spinal cord, but large rhabdoid/epi… (full text at CIViC) PMID 34464935 · Chen et al., 2021 · Open in CIViC | civic |