Publication
Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.
Authors not recorded
Cancer Cell2014PMID 25453902PMC4327935stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerAlveolar Soft Part Sarcomacivic_curation1.00
- geneTFE3civic_curation1.00
- variantTFE3 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25453902
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| TFE3 Fusion1 | ||||||||
| (oncogenic) | Alveolar Soft Part Sarcoma | Oncogenic | D | Supports Oncogenicity | 4 | accepted | EID9883Goodwin, et al. (2014) presented in vivo study on mice carrying the ASPSCR1-TFE3 fusion gene. The results showed that Rosa26-LSL-AT3/CreER mice expressed tumors histological equal to the human’s alveo… (full text at CIViC) PMID 25453902 · Goodwin et al., 2014 · Open in CIViC | civic |