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Connective and Soft Tissue Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Connective and Soft Tissue Neoplasm

Cancer Family

Connective and Soft Tissue Neoplasm

CI-CAN-00000010Explore in graph →

Non-malignant848 active trials17 approved drugs339 evidence items

NCIt: C3810
MeSH: D018204

Overview
Statistics
Survival
Genomics24
Variants & evidence339
Drugs43
Trials3876
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (225)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 201–225 of 225 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Targeting Fibroblast Growth Factor Receptor 1 for Treatment of Soft-Tissue Sarcoma.
· Clin Cancer Res · 2017 · PMID 27535980 · validated civic_curation pubmed
A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas.
· Cell Death Dis · 2016 · PMID 27735949 · validated civic_curation pubmed
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.
· Cancer Discov · 2017 · PMID 28446439 · validated civic_curation pubmed
Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor.
· Cancer Biol Ther · 2016 · PMID 26650448 · validated civic_curation pubmed
p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3.
· Mol Cancer Ther · 2007 · PMID 17363498 · validated civic_curation pubmed
A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.
· Clin Cancer Res · 2013 · PMID 23231951 · validated civic_curation pubmed
HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.
· J Pathol Clin Res · 2016 · PMID 27499916 · validated

Showing 201–225 of 225 publications

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civic_curation

Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.

· PLoS One · 2016 · PMID 27391784 · validated civic_curation pubmed

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.

· Oncotarget · 2016 · PMID 27286459 · validated civic_curation pubmed

CDKN2A/p16 Loss Implicates CDK4 as a Therapeutic Target in Imatinib-Resistant Dermatofibrosarcoma Protuberans.

· Mol Cancer Ther · 2015 · PMID 25852058 · validated civic_curation pubmed

Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy.

· PLoS One · 2017 · PMID 28672024 · validated civic_curation pubmed

FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma.

· Clin Cancer Res · 2017 · PMID 28637688 · validated civic_curation pubmed

Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.

· Clin Cancer Res · 2014 · PMID 24963049 · validated civic_curation pubmed

Painter et al. Nat Med 2020

· 2020 · PMID 32042194 · validated cbioportal_study pubmed

Josephine K et al. Cancer Research 2024

· 2024 · PMID 38335254 · validated cbioportal_study pubmed

Tirode et al. Cancer Discov 2014

· 2014 · PMID 25223734 · validated cbioportal_study pubmed

Diana et al. NPJ Precis Oncol 2023

· 2023 · PMID 36593350 · validated cbioportal_study pubmed

Dermawan et al. Clin Cancer Res 2023

· 2023 · PMID 37477937 · validated cbioportal_study pubmed

Farshad et al. Nature 2021

· 2021 · PMID 34433969 · validated cbioportal_study pubmed

Lee et al. Nat Genet 2014

· 2014 · PMID 25240281 · validated cbioportal_study pubmed

de Wardin et al. JCO Precis Oncol 2023

· 2023 · PMID 37315267 · validated cbioportal_study pubmed

Wardin et at. NPJ Precis Oncol 2023

· 2023 · PMID 37730754 · validated cbioportal_study pubmed

Dermawan JK et al. Sci Adv 2026

· 2026 · PMID 41758938 · validated cbioportal_study pubmed

Cyrta et al. 2022 Cold Spring Harb Mol Case Stud 8: a006227

· 2022 · PMID 36577525 · validated cbioportal_study pubmed

Hensley et al. Clin Cancer Res 2020

· 2020 · PMID 32299819 · validated cbioportal_study pubmed